AlkB Homolog 5, RNA Demethylase [alfa-ketoglutarát-dependentní dioxygenasa, AlkB homolog 5]

topical
4
Terms

alfa ketoglutarát dependentní dioxygenáza, AlkB homolog 5
RNA-demetyláza ALKBH5

 

Alkylated DNA Repair Protein AlkB Homolog 5
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5
RNA Demethylase ALKBH5

Definition

A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.

DUI
D000071502 MeSH Browser
CUI
M000614944
Previous indexing
Dioxygenases (2011-2016)
History note
2017
Public note
2017

D Chemicals and Drugs
D08.811 Enzymes 1 549
D08.811.074 DNA Repair Enzymes 61
D08.811.074.062 AlkB Enzymes
D08.811.074.062.937 AlkB Homolog 5, RNA Demethylase 4
D08.811.682 Oxidoreductases 446
D08.811.682.662.582 Oxidoreductases, N-Demethylating 10
D08.811.682.662.582.138 AlkB Homolog 4, Lysine Demethylase
D08.811.682.662.582.207 AlkB Homolog 5, RNA Demethylase 4
D08.811.682.662.582.276 Aminopyrine N-Demethylase
D08.811.682.662.582.338 Cytochrome P-450 CYP2E1 39
D08.811.682.662.582.353 Cytochrome P-450 CYP3A 131
D08.811.682.662.582.361 Dihydropteridine Reductase 1
D08.811.682.662.582.369 Dimethylglycine Dehydrogenase
D08.811.682.662.582.400 Ethylmorphine-N-Demethylase
D08.811.682.662.582.475 Histone Demethylases 16
D08.811.682.662.582.550 Sarcosine Dehydrogenase 1
D08.811.682.662.582.700 Sarcosine Oxidase 1
D08.811.682.690 Oxygenases 76
D08.811.682.690.416 Dioxygenases 18
D08.811.682.690.416.139 AlkB Enzymes
D08.811.682.690.416.139.500 AlkB Homolog 1, Histone H2a Dioxygenase
D08.811.682.690.416.139.937 AlkB Homolog 4, Lysine Demethylase
D08.811.682.690.416.139.968 AlkB Homolog 5, RNA Demethylase 4
D08.811.682.690.416.139.984 AlkB Homolog 8, tRNA Methyltransferase 1

ALKBH5 protein, human Chemical MeSH Browser

ALKBH5 protein, mouse Chemical MeSH Browser

ALKBH5 protein, zebrafish Chemical MeSH Browser