2-Isopropylmalate Synthase [2-isopropylmalátsynthasa]
- Terms
-
2-isopropylmalát syntasa
2-isopropylmalát syntáza
alfa-isopropylmalát syntasa
α-isopropylmalát syntasa
-
alpha-Isopropylmalate Synthase
An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.
- DUI
- D015079 MeSH Browser
- CUI
- M0023192
- CAS
- 3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)
- Previous indexing
- Ketoacid-Lyases (1973-1974); Ketoacids (1973-1974); Malates (1973-1974)
- History note
- 91(75); was see under KETOACID-LYASES 1975-90
- Public note
- 91; was see under KETOACID-LYASES 1975-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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