2-Isopropylmalate Synthase [2-isopropylmalátsynthasa]

topical
Terms

2-isopropylmalát syntasa
2-isopropylmalát syntáza
alfa-isopropylmalát syntasa
α-isopropylmalát syntasa

 

alpha-Isopropylmalate Synthase

Persistent link   https://www.medvik.cz/link/D015079
Definition

An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE, forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. This enzyme was formerly listed as EC 4.1.3.12.

DUI
D015079 MeSH Browser
CUI
M0023192
RN
EC 2.3.3.13
CAS
3-Carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating)
Previous indexing
Ketoacid-Lyases (1973-1974); Ketoacids (1973-1974); Malates (1973-1974)
History note
91(75); was see under KETOACID-LYASES 1975-90
Public note
91; was see under KETOACID-LYASES 1975-90

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.050 Acyltransferases 169
D08.811.913.050.080 Acetyl-CoA C-Acyltransferase 4
D08.811.913.050.134 Acetyltransferases 54
D08.811.913.050.200 Aminoacyltransferases 4
D08.811.913.050.276 5-Aminolevulinate Synthetase 4
D08.811.913.050.331 ATP Citrate (pro-S)-Lyase 7
D08.811.913.050.350 Carnitine Acyltransferases 1
D08.811.913.050.368 Citrate (si)-Synthase 32
D08.811.913.050.614 2-Isopropylmalate Synthase
D08.811.913.050.618 Malate Synthase 1
D08.811.913.050.668 Serine C-Palmitoyltransferase 5
D08.811.913.050.712 Sphingosine N-Acyltransferase 4
D08.811.913.050.799 Sterol O-Acyltransferase 12
D10 Lipids 2 523