Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

DUI

D015345 MeSH Browser

CUI

M0023630

Previous indexing

Oligonucleotides (1972-1988); Nucleic Acid Hybridization (1972-1988)

History note

89

Public note

89