Signal Transduction [signální transdukce]
- Terms
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buněčná signalizace
receptory zprostředkovaný přenos signálů
signálně transdukční dráhy
signální cesty
signální dráhy
signální transdukční systém
signální transdukční systémy
signály - přenos
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Cell Signaling
Receptor Mediated Signal Transduction
Receptor-Mediated Signal Transduction
Signal Pathways
Signal Transduction Pathways
Signal Transduction Systems
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
- DUI
- D015398 MeSH Browser
- CUI
- M0023729
- Previous indexing
- Membrane Potentials (1977-1988); specific compounds/physiology (1977-1988)
- History note
- 89
- Public note
- 89
Allowable subheadings
IKBIP protein, human Chemical MeSH Browser
NEVER-RIPE protein, Lycopersicon esculentum Chemical MeSH Browser