Signal Transduction [signální transdukce]

topical
2 228
Terms

buněčná signalizace
receptory zprostředkovaný přenos signálů
signálně transdukční dráhy
signální cesty
signální dráhy
signální transdukční systém
signální transdukční systémy
signály - přenos

 

Cell Signaling
Receptor Mediated Signal Transduction
Receptor-Mediated Signal Transduction
Signal Pathways
Signal Transduction Pathways
Signal Transduction Systems

Persistent link   https://www.medvik.cz/link/D015398
Definition

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

DUI
D015398 MeSH Browser
CUI
M0023729
Previous indexing
Membrane Potentials (1977-1988); specific compounds/physiology (1977-1988)
History note
89
Public note
89

Allowable subheadings

DE
drug effects 482
GE
genetics 179
IM
immunology 72
PH
physiology 314
RE
radiation effects 13

G Phenomena and Processes
G02 Chemical Phenomena 308
G02.111 Biochemical Phenomena 370
G02.111.007 Acid-Base Equilibrium 447
G02.111.012 Acylation 24
G02.111.017 Aerobiosis 73
G02.111.026 Agglutination 53
G02.111.035 Alkylation 65
G02.111.044 Allosteric Regulation 71
G02.111.053 Amination 7
G02.111.062 Anaerobiosis 143
G02.111.071 Autotrophic Processes 13
G02.111.080 Base Composition 127
G02.111.084 Binding, Competitive 61
G02.111.086 Biocatalysis 83
G02.111.087 Biochemical Processes obsolete
G02.111.092 Biomineralization 4
G02.111.098 Biosynthetic Pathways 51
G02.111.109 Biotinylation 20
G02.111.130 Body Composition 542
G02.111.150 Brain Chemistry 424
G02.111.158 Carbohydrate Metabolism 493
G02.111.165 Citric Acid Cycle 57
G02.111.180 Cyclization 55
G02.111.188 Dealkylation 4
G02.111.192 Deamination 10
G02.111.195 Decarboxylation 17
G02.111.210 DNA Cleavage 15
G02.111.218 DNA Methylation 448
G02.111.222 DNA Repair 476
G02.111.225 DNA Replication 290
G02.111.240 Down-Regulation 301
G02.111.248 Electron Transport 161
G02.111.255 Energy Transfer 323
G02.111.263 Enzyme Activation 380
G02.111.270 Esterification 62
G02.111.323 Halogenation 45
G02.111.375 Heterotrophic Processes 20
G02.111.380 Hydrogenation 24
G02.111.385 Hydroxylation 65
G02.111.490 Kinetics 1 105
G02.111.515 Lipid Peroxidation 760
G02.111.528 Lipogenesis 58
G02.111.534 Lipolysis 181
G02.111.540 Lipoylation 11
G02.111.545 Melanogenesis
G02.111.550 Membrane Fluidity 83
G02.111.560 Molecular Mimicry 39
G02.111.570 Molecular Structure 1 339
G02.111.587 Nitrogen Cycle 6
G02.111.595 Nitrosation 12
G02.111.603 Nucleic Acid Denaturation 62
G02.111.611 Nucleic Acid Hybridization 172
G02.111.619 Nucleic Acid Renaturation 2
G02.111.635 Osmoregulation 11
G02.111.655 Osmosis 77
G02.111.660 Peptide Biosynthesis 43
G02.111.665 Phosphorylation 723
G02.111.669 Phototrophic Processes 25
G02.111.672 Prenylation 14
G02.111.675 Protein Aggregation, Pathological 17
G02.111.679 Protein Binding 1 256
G02.111.688 Protein Folding 109
G02.111.691 Protein Modification, Translational 7
G02.111.694 Protein Multimerization 124
G02.111.700 Protein Stability 96
G02.111.720 Proteolysis 130
G02.111.730 Proteostasis 7
G02.111.740 RNA Cleavage 6
G02.111.750 RNA Folding 5
G02.111.760 RNA Processing, Post-Transcriptional 57
G02.111.770 RNA Replication
G02.111.780 RNA Stability 46
G02.111.810 Sequence Homology 74
G02.111.820 Signal Transduction 2 228
G02.111.820.200 Hippo Signaling Pathway 2
G02.111.820.400 Ion Channel Gating 104
G02.111.820.480 Light Signal Transduction 5
G02.111.820.560 MAP Kinase Signaling System 134
G02.111.820.580 Mechanotransduction, Cellular 37
G02.111.820.690 Non-Neuronal Cholinergic System
G02.111.820.800 Second Messenger Systems 25
G02.111.820.850 Synaptic Transmission 501
G02.111.820.925 Wnt Signaling Pathway 97
G02.111.830 Structure-Activity Relationship 1 830
G02.111.833 Substrate Cycling 1
G02.111.835 Substrate Specificity 335
G02.111.873 Transcription, Genetic 660
G02.111.905 Up-Regulation 377
G04 Cell Physiological Phenomena 515
G04.011 Autophagy 188
G04.022 Cell Adhesion 363
G04.033 Cell Competition
G04.043 Cellular Senescence 238
G04.085 Cell Communication 219
G04.128 Cell Compartmentation 35
G04.140 Cell Count 209
G04.144 Cell Cycle 729
G04.146 Cell Death 378
G04.148 Cell Dedifferentiation 20
G04.152 Cell Differentiation 1 408
G04.155 Cell Fusion 44
G04.161 Cell Growth Processes 49
G04.165 Cell-in-Cell Formation 2
G04.172 Cell Lineage 91
G04.175 Cell Membrane Permeability 391
G04.198 Cell Movement 429
G04.250 Cell Polarity 49
G04.270 Cell Respiration 105
G04.299 Cell Physiological Processes obsolete
G04.320 Cell Shape 61
G04.325 Cell Size 68
G04.346 Cell Survival 1 062
G04.356 Cell Transdifferentiation 17
G04.366 Cellular Microenvironment 24
G04.375 Clonal Evolution 28
G04.383 Contact Inhibition 6
G04.392 Cytoplasmic Streaming
G04.400 DNA Packaging 3
G04.417 Endocytosis 112
G04.434 Endoplasmic Reticulum Stress 55
G04.468 Exocytosis 52
G04.502 Lymphocyte Cooperation 8
G04.536 Melanogenesis
G04.570 Membrane Fluidity 83
G04.575 Membrane Fusion 27
G04.580 Membrane Potentials 543
G04.590 Mitochondrial Swelling 11
G04.599 Mitochondrial Turnover 5
G04.618 Organelle Biogenesis 87
G04.655 Organelle Shape 1
G04.670 Organelle Size 3
G04.712 Radiation Tolerance 167
G04.753 Re-Epithelialization 23
G04.774 Receptor Aggregation 4
G04.794 Receptor Cross-Talk 65
G04.835 Signal Transduction 2 228
G04.835.199 Excitation Contraction Coupling 11
G04.835.300 Hippo Signaling Pathway 2
G04.835.400 Ion Channel Gating 104
G04.835.480 Light Signal Transduction 5
G04.835.560 MAP Kinase Signaling System 134
G04.835.580 Mechanotransduction, Cellular 37
G04.835.690 Non-Neuronal Cholinergic System
G04.835.800 Second Messenger Systems 25
G04.835.850 Synaptic Transmission 501
G04.835.925 Wnt Signaling Pathway 97
G04.917 Trogocytosis 1

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