Granulocyte Colony-Stimulating Factor [faktor stimulující kolonie granulocytů]

topical
190
Terms

granulocyty stimulující faktor

 

Colony-Stimulating Factor, Granulocyte
G-CSF
Myeloid Growth Factor

Persistent link   https://www.medvik.cz/link/D016179
Definition

A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

DUI
D016179 MeSH Browser
CUI
M0024696
Previous indexing
Colony-Stimulating Factors (1976-1990)
History note
91
Public note
91

Allowable subheadings

AD
administration & dosage 49
AE
adverse effects 15
AG
agonists
AN
analysis 1
AI
antagonists & inhibitors 2
BI
biosynthesis 3
BL
blood 8
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification 5
DF
deficiency
DE
drug effects 3
EC
economics 7
GE
genetics 1
HI
history 1
IM
immunology 3
IP
isolation & purification 1
ME
metabolism 5
PK
pharmacokinetics 4
PD
pharmacology 45
PH
physiology 2
PO
poisoning
RE
radiation effects
ST
standards 1
SD
supply & distribution
TU
therapeutic use 102
TO
toxicity 1
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D09 Carbohydrates 723
D09.400 Glycoconjugates 58
D09.400.430 Glycoproteins 637
D09.400.430.775 Colony-Stimulating Factors 19
D09.400.430.775.150 Erythropoietin 614
D09.400.430.775.200 Granulocyte Colony-Stimulating Factor 190
D09.400.430.775.200.500 Filgrastim 27
D09.400.430.775.200.750 Lenograstim
D09.400.430.775.300 Granulocyte-Macrophage Colony-Stimulating Factor 78
D09.400.430.775.400 Interleukin-3 11
D09.400.430.775.500 Macrophage Colony-Stimulating Factor 14
D09.400.430.775.750 Thrombopoietin 29
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 382
D12.644.276 Intercellular Signaling Peptides and Proteins 156
D12.644.276.374 Cytokines 2 154
D12.644.276.374.410 Hematopoietic Cell Growth Factors 54
D12.644.276.374.410.240 Colony-Stimulating Factors 19
D12.644.276.374.410.240.150 Erythropoietin 614
D12.644.276.374.410.240.350 Granulocyte Colony-Stimulating Factor 190
D12.644.276.374.410.240.350.500 Filgrastim 27
D12.644.276.374.410.240.350.750 Lenograstim
D12.644.276.374.410.240.375 Granulocyte-Macrophage Colony-Stimulating Factor 78
D12.644.276.374.410.240.400 Interleukin-3 11
D12.644.276.374.410.240.500 Macrophage Colony-Stimulating Factor 14
D12.644.276.374.410.240.750 Thrombopoietin 29
D12.776 Proteins 2 577
D12.776.395 Glycoproteins 637
D12.776.395.240 Colony-Stimulating Factors 19
D12.776.395.240.150 Erythropoietin 614
D12.776.395.240.200 Granulocyte Colony-Stimulating Factor 190
D12.776.395.240.200.500 Filgrastim 27
D12.776.395.240.200.750 Lenograstim
D12.776.395.240.300 Granulocyte-Macrophage Colony-Stimulating Factor 78
D12.776.395.240.400 Interleukin-3 11
D12.776.395.240.500 Macrophage Colony-Stimulating Factor 14
D12.776.395.240.750 Thrombopoietin 29
D12.776.467 Intercellular Signaling Peptides and Proteins 156
D12.776.467.374 Cytokines 2 154
D12.776.467.374.410 Hematopoietic Cell Growth Factors 54
D12.776.467.374.410.240 Colony-Stimulating Factors 19
D12.776.467.374.410.240.150 Erythropoietin 614
D12.776.467.374.410.240.350 Granulocyte Colony-Stimulating Factor 190
D12.776.467.374.410.240.350.500 Filgrastim 27
D12.776.467.374.410.240.350.750 Lenograstim
D12.776.467.374.410.240.375 Granulocyte-Macrophage Colony-Stimulating Factor 78
D12.776.467.374.410.240.400 Interleukin-3 11
D12.776.467.374.410.240.500 Macrophage Colony-Stimulating Factor 14
D12.776.467.374.410.240.750 Thrombopoietin 29
D23 Biological Factors 143
D23.529 Intercellular Signaling Peptides and Proteins 156
D23.529.374 Cytokines 2 154
D23.529.374.410 Hematopoietic Cell Growth Factors 54
D23.529.374.410.240 Colony-Stimulating Factors 19
D23.529.374.410.240.150 Erythropoietin 614
D23.529.374.410.240.350 Granulocyte Colony-Stimulating Factor 190
D23.529.374.410.240.350.500 Filgrastim 27
D23.529.374.410.240.350.750 Lenograstim
D23.529.374.410.240.375 Granulocyte-Macrophage Colony-Stimulating Factor 78
D23.529.374.410.240.400 Interleukin-3 11
D23.529.374.410.240.500 Macrophage Colony-Stimulating Factor 14
D23.529.374.410.240.750 Thrombopoietin 29

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