geny mos [Genes, mos]

tematický
4
Termíny

geny c-mos
geny v-mos
onkogeny mos
onkogeny v-mos
protoonkogeny c-mos
protoonkogeny mos

 

c-mos Genes
c-mos Proto-Oncogenes
mos Genes
mos Oncogenes
mos Proto-Oncogenes
v-mos Genes
v-mos Oncogenes

Perzistentní odkaz   https://www.medvik.cz/link/D016258
Definice

DNA sekvence související s retroviry (mos), které byly původně izolovány z Moloneyho viru myšího sarkomu (Mo-MSV). Protoonkogen mos (c-mos) kóduje protein, který je členem rodiny serinkináz. Dosud se neprokázalo, že se lidský c-mos může transformovat nebo je tumorigenní. U myší může ale nastat aktivace po inzerci intracisternální částice podobné retroviru do blízkosti sekvence c-mos. Lidský gen c-mos se nachází na dlouhém raménku chromozomu 8 (8q22).

Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c-mos can become transformed or has a role in human cancer. However, in mice, activation can occur when the retrovirus-like intracisternal A-particle inserts itself near the c-mos sequence. The human c-mos gene is located at 8q22 on the long arm of chromosome 8.

Anotace
mos stands for "MOloney Sarcoma"
DUI
D016258 MeSH Prohlížeč
CUI
M0024841
Předchozí užití
Oncogenes (1983-1985); Proto-Oncogenes (1986-1990); Genes, Viral (1982)
Historická pozn.
91
Veřejná pozn.
91

G Jevy a procesy
G03 metabolické jevy zastaralé
G05.360.340 genom 361
G05.360.340.024 komponenty genomu 13
G05.360.340.024.340 geny 673
G05.360.340.024.340.375 geny nádorové 34
G05.360.340.024.340.375.500 onkogeny 238
G05.360.340.024.340.375.500.791 protoonkogeny 54
G05.360.340.024.340.375.500.791.100 geny abl 21
G05.360.340.024.340.375.500.791.148 geny bcl-1 4
G05.360.340.024.340.375.500.791.150 geny bcl-2 61
G05.360.340.024.340.375.500.791.290 geny erbA 1
G05.360.340.024.340.375.500.791.295 geny erbB 29
G05.360.340.024.340.375.500.791.325 geny fms
G05.360.340.024.340.375.500.791.330 geny fos 15
G05.360.340.024.340.375.500.791.365 geny jun 4
G05.360.340.024.340.375.500.791.400 geny mos 4
G05.360.340.024.340.375.500.791.418 geny myb 18
G05.360.340.024.340.375.500.791.420 geny myc 45
G05.360.340.024.340.375.500.791.550 geny ras 207
G05.360.340.024.340.375.500.791.552 geny rel
G05.360.340.024.340.375.500.791.560 geny sis
G05.360.340.024.340.375.500.791.570 geny src 23