geny mos [Genes, mos]

tematický
4
Termíny

geny c-mos
geny v-mos
onkogeny mos
onkogeny v-mos
protoonkogeny c-mos
protoonkogeny mos

 

c-mos Genes
c-mos Proto-Oncogenes
mos Genes
mos Oncogenes
mos Proto-Oncogenes
v-mos Genes
v-mos Oncogenes

Perzistentní odkaz   https://www.medvik.cz/link/D016258
Definice

DNA sekvence související s retroviry (mos), které byly původně izolovány z Moloneyho viru myšího sarkomu (Mo-MSV). Protoonkogen mos (c-mos) kóduje protein, který je členem rodiny serinkináz. Dosud se neprokázalo, že se lidský c-mos může transformovat nebo je tumorigenní. U myší může ale nastat aktivace po inzerci intracisternální částice podobné retroviru do blízkosti sekvence c-mos. Lidský gen c-mos se nachází na dlouhém raménku chromozomu 8 (8q22).

Retrovirus-associated DNA sequences (mos) originally isolated from the Moloney murine sarcoma virus (Mo-MSV). The proto-oncogene mos (c-mos) codes for a protein which is a member of the serine kinase family. There is no evidence as yet that human c-mos can become transformed or has a role in human cancer. However, in mice, activation can occur when the retrovirus-like intracisternal A-particle inserts itself near the c-mos sequence. The human c-mos gene is located at 8q22 on the long arm of chromosome 8.

Anotace
mos stands for "MOloney Sarcoma"
DUI
D016258 MeSH Prohlížeč
CUI
M0024841
Předchozí užití
Oncogenes (1983-1985); Proto-Oncogenes (1986-1990); Genes, Viral (1982)
Historická pozn.
91
Veřejná pozn.
91

G Jevy a procesy
G03 metabolické jevy zastaralé
G03 metabolismus 1 204
G05.360.340 genom 369
G05.360.340.024 komponenty genomu 13
G05.360.340.024.340 geny 676
G05.360.340.024.340.375 geny nádorové 34
G05.360.340.024.340.375.500 onkogeny 240
G05.360.340.024.340.375.500.791 protoonkogeny 54
G05.360.340.024.340.375.500.791.100 geny abl 22
G05.360.340.024.340.375.500.791.148 geny bcl-1 4
G05.360.340.024.340.375.500.791.150 geny bcl-2 61
G05.360.340.024.340.375.500.791.290 geny erbA 1
G05.360.340.024.340.375.500.791.295 geny erbB 32
G05.360.340.024.340.375.500.791.325 geny fms
G05.360.340.024.340.375.500.791.330 geny fos 15
G05.360.340.024.340.375.500.791.365 geny jun 4
G05.360.340.024.340.375.500.791.400 geny mos 4
G05.360.340.024.340.375.500.791.418 geny myb 18
G05.360.340.024.340.375.500.791.420 geny myc 45
G05.360.340.024.340.375.500.791.550 geny ras 212
G05.360.340.024.340.375.500.791.552 geny rel
G05.360.340.024.340.375.500.791.560 geny sis
G05.360.340.024.340.375.500.791.570 geny src 23