Genes, bcl-2 [geny bcl-2]

topical
61
Terms

geny c-bcl-2
protoonkogeny c-bcl-2

 

bcl-2 Genes
c-bcl-2 Genes
c-bcl-2 Proto-Oncogenes

Persistent link   https://www.medvik.cz/link/D019254
Definition

The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.

Annotation
bcl stands for "B-Cell Leukemia"
DUI
D019254 MeSH Browser
CUI
M0028675
Previous indexing
Oncogenes (1984-1996); Proto-Oncogenes (1988-1996)
History note
97
Public note
97

Allowable subheadings

DE
drug effects 8
ES
ethics
GE
genetics 13
IM
immunology 4
PH
physiology 12
RE
radiation effects 1

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G05.360 Genetic Structures 25
G05.360.340 Genome 361
G05.360.340.024 Genome Components 13
G05.360.340.024.340 Genes 673
G05.360.340.024.340.375 Genes, Neoplasm 34
G05.360.340.024.340.375.500 Oncogenes 238
G05.360.340.024.340.375.500.791 Proto-Oncogenes 54
G05.360.340.024.340.375.500.791.100 Genes, abl 21
G05.360.340.024.340.375.500.791.148 Genes, bcl-1 4
G05.360.340.024.340.375.500.791.150 Genes, bcl-2 61
G05.360.340.024.340.375.500.791.290 Genes, erbA 1
G05.360.340.024.340.375.500.791.295 Genes, erbB 29
G05.360.340.024.340.375.500.791.325 Genes, fms
G05.360.340.024.340.375.500.791.330 Genes, fos 15
G05.360.340.024.340.375.500.791.365 Genes, jun 4
G05.360.340.024.340.375.500.791.400 Genes, mos 4
G05.360.340.024.340.375.500.791.418 Genes, myb 18
G05.360.340.024.340.375.500.791.420 Genes, myc 45
G05.360.340.024.340.375.500.791.550 Genes, ras 209
G05.360.340.024.340.375.500.791.552 Genes, rel
G05.360.340.024.340.375.500.791.560 Genes, sis
G05.360.340.024.340.375.500.791.570 Genes, src 23
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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