geny bcl-2 [Genes, bcl-2]

tematický
61
Termíny

geny c-bcl-2
protoonkogeny c-bcl-2

 

bcl-2 Genes
c-bcl-2 Genes
c-bcl-2 Proto-Oncogenes

Perzistentní odkaz   https://www.medvik.cz/link/D019254
Definice

Geny asociované s některými druhy leukémií. V normálních buňkách blokují apoptózu, nadměrná exprese souvisí s folikulárním lymfomem. Nadměrnou expresi vyvolává translokace t(14;18). Lidský gen c-bcl-2 se nachází na dlouhém raménku chromozomu 18 (18q24).

The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.

Anotace
bcl stands for "B-Cell Leukemia"
DUI
D019254 MeSH Prohlížeč
CUI
M0028675
Předchozí užití
Oncogenes (1984-1996); Proto-Oncogenes (1988-1996)
Historická pozn.
97
Veřejná pozn.
97

G Jevy a procesy
G03 metabolické jevy zastaralé
G03 metabolismus 1 197
G05.360.340 genom 361
G05.360.340.024 komponenty genomu 13
G05.360.340.024.340 geny 673
G05.360.340.024.340.375 geny nádorové 34
G05.360.340.024.340.375.500 onkogeny 238
G05.360.340.024.340.375.500.791 protoonkogeny 54
G05.360.340.024.340.375.500.791.100 geny abl 21
G05.360.340.024.340.375.500.791.148 geny bcl-1 4
G05.360.340.024.340.375.500.791.150 geny bcl-2 61
G05.360.340.024.340.375.500.791.290 geny erbA 1
G05.360.340.024.340.375.500.791.295 geny erbB 29
G05.360.340.024.340.375.500.791.325 geny fms
G05.360.340.024.340.375.500.791.330 geny fos 15
G05.360.340.024.340.375.500.791.365 geny jun 4
G05.360.340.024.340.375.500.791.400 geny mos 4
G05.360.340.024.340.375.500.791.418 geny myb 18
G05.360.340.024.340.375.500.791.420 geny myc 45
G05.360.340.024.340.375.500.791.550 geny ras 209
G05.360.340.024.340.375.500.791.552 geny rel
G05.360.340.024.340.375.500.791.560 geny sis
G05.360.340.024.340.375.500.791.570 geny src 23