Antigenic Modulation [antigenní modulace]

topical
11
Persistent link   https://www.medvik.cz/link/D016525
Definition

Loss of detectable antigen from the surface of a cell after incubation with antibodies. This is one method in which some tumors escape detection by the immune system. Antigenic modulation of target antigens also reduces the therapeutic effectiveness of treatment by monoclonal antibodies.

DUI
D016525 MeSH Browser
CUI
M0025224
Previous indexing
Antigen-Antibody Reactions (1968-1989); Antigens, Surface/analysis (1979-1991); Antigens, Surface/immunology (1979-1988)
History note
92
Public note
92

Allowable subheadings

DE
drug effects 0
ES
ethics 0
GE
genetics 3
IM
immunology 4
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G12.122 Antigen-Antibody Reactions 393
G12.122.100 Agglutination 53
G12.122.125 Antibody Affinity 39
G12.122.140 Antigenic Modulation 11
G12.122.232 Binding Sites, Antibody 28
G12.122.281 Cross Reactions 186
G12.122.545 Hemolysis 382
G12.122.612 Immunologic Capping 1
G12.122.754 Passive Cutaneous Anaphylaxis 8
G12.122.780 Rh Isoimmunization 81
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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