A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

DUI

D017239 MeSH Browser

CUI

M0026156

CAS

Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,1-2alpha,12aalpha,12balpha))-

Previous indexing

Alkaloids (1982-1992); Terpenes (1977-1981)

History note

95; was TAXOL 1993-94; was TAXOL A (NM) 1977-92

Online note

use PACLITAXEL to search TAXOL 1993-94; use PACLITAXEL (NM) to search TAXOL A 1977-92

Public note

95; was TAXOL 1993-94; TAXOL A was indexed under ALKALOIDS 1982-92 & TERPENES 1977-81