B7-1 Antigen [antigeny CD80]
- Terms
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antigen B7-1
antigen CD80
molekula B7-1
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Antigen, B7-1
Antigens, CD80
B-Cell Activation Antigen
B7-1 Costimulatory Molecule
B7-1 Ligand
CD80 Antigen
CD80 Antigens
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
- DUI
- D018122 MeSH Browser
- CUI
- M0027327
- Previous indexing
- Antigens, Surface (1991-1993)
- History note
- 2018 (1991)
- Public note
- 2018; see ANTIGENS, CD80 1996-2017; see B-CELL ACTIVATION ANTIGEN 1994-95; B7-1 ANTIGEN was indexed under B-CELL ACTIVATION ANTIGEN 1994-95; B CELL ACTIVATION ANTIGEN B7 was indexed under ANTIGENS, SURFACE 1991-93
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 2
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 5
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 2
- EC
- economics
- GE
- genetics 5
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 5
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 2
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
CD80 protein, human Chemical MeSH Browser