geny BRCA1 [Genes, BRCA1]

tematický
279
Termíny

BRCA1 gen
BRCA1 geny
gen BRCA1

 

BRCA1 Gene

Perzistentní odkaz   https://www.medvik.cz/link/D019398
Definice

Tumor supresorový gen umístěný na lidském chromozomu 17, na lokusu 17q21. Mutace tohoto genu je spojena s dědičným syndromem nádoru prsu a vaječníků. Kóduje velký jaderný protein, který je součástí systému opravy DNA.

A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.

Anotace
BRCA stands for "BReast CAncer"
DUI
D019398 MeSH Prohlížeč
CUI
M0028862
Předchozí užití
Genes, Suppressor, Tumor (1993-1996)
Historická pozn.
97
Veřejná pozn.
97

Povolená podhesla

PH
fyziologie 11
DE
účinky léků 22
RE
účinky záření 1

G Jevy a procesy
G05 genetické jevy 133
G05.360 genetické struktury 25
G05.360.340 genom 361
G05.360.340.024 komponenty genomu 13
G05.360.340.024.340 geny 673
G05.360.340.024.340.375 geny nádorové 32
G05.360.340.024.340.375.249 tumor supresorové geny 163
G05.360.340.024.340.375.249.050 geny APC 40
G05.360.340.024.340.375.249.100 geny BRCA1 279
G05.360.340.024.340.375.249.105 geny BRCA2 248
G05.360.340.024.340.375.249.200 geny DCC 2
G05.360.340.024.340.375.249.320 geny MCC
G05.360.340.024.340.375.249.340 geny neurofibromatózy 1 14
G05.360.340.024.340.375.249.345 geny neurofibromatózy 2 1
G05.360.340.024.340.375.249.375 geny p16 20
G05.360.340.024.340.375.249.385 geny p53 262
G05.360.340.024.340.375.249.400 geny retinoblastomu 15
G05.360.340.024.340.375.249.420 geny Wilmsova nádoru 20
G05.360.340.024.340.415 geny recesivní 49
G05.360.340.024.340.415.400 tumor supresorové geny 163
G05.360.340.024.340.415.400.050 geny APC 40
G05.360.340.024.340.415.400.100 geny BRCA1 279
G05.360.340.024.340.415.400.105 geny BRCA2 248
G05.360.340.024.340.415.400.200 geny DCC 2
G05.360.340.024.340.415.400.320 geny MCC
G05.360.340.024.340.415.400.340 geny neurofibromatózy 1 14
G05.360.340.024.340.415.400.345 geny neurofibromatózy 2 1
G05.360.340.024.340.415.400.375 geny p16 20
G05.360.340.024.340.415.400.385 geny p53 262
G05.360.340.024.340.415.400.400 geny retinoblastomu 15
G05.360.340.024.340.415.400.420 geny Wilmsova nádoru 20

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