Loss of Heterozygosity [ztráta heterozygozity]

topical
60
Terms

ztráta alely
ztráta heterozygotnosti

 

Allelic Loss
Heterozygosity, Loss of

Persistent link   https://www.medvik.cz/link/D019656
Definition

The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.

Annotation
do not confuse entry term ALLELIC LOSS with ALLELIC IMBALANCE
DUI
D019656 MeSH Browser
CUI
M0029159
Previous indexing
Chromosome Deletion (1987-1997); Heterozygote (1983-1997)
History note
98
Public note
98

Allowable subheadings

DE
drug effects
GE
genetics 12
IM
immunology 2
PH
physiology 1
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G05.365 Genetic Variation 858
G05.365.590 Mutation 4 997
G05.365.590.029 Allelic Imbalance 2
G05.365.590.029.530 Loss of Heterozygosity 60
G05.365.590.029.530.175 Chromosome Deletion 199
G05.365.590.029.530.587 Haploinsufficiency 16
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

Add

Narrower terms