Tissue Inhibitor of Metalloproteinases [tkáňové inhibitory metaloproteinas]
topical
51
- Terms
-
metaloproteinasy - tkáňové inhibitory
proteiny TIMP
tkáňové inhibitory metaloproteináz
-
TIMP Proteins
Tissue Inhibitor of Metalloproteinase
Persistent link
https://www.medvik.cz/link/D019714
Definition
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.
- Annotation
- general or unspecified; prefer specifics
- DUI
- D019714 MeSH Browser
- CUI
- M0029270
- Previous indexing
- Enzyme Inhibitors (1989-1997); Glycoproteins (1980-1990)
- History note
- 98; see TISSUE INHIBITOR OF METALLOPROTEINASES (NM) 1980-97
- Public note
- 98; COLLAGENASE INHIBITOR (now TISSUE INHIBITOR OF METALLOPROTEINASES) was indexed under GLYCOPROTEINS 1989-97 & ENZYME INHIBITORS 1980-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 6
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood 7
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification 2
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 6
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 8
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology 5
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.776.815.468
Protease Nexins
D12.776.815.688
Serine Peptidase Inhibitors, Kazal Type
D12.776.815.875.775
Tissue Inhibitor of Metalloproteinase-4
TIMP protein, Crassostrea gigas Chemical MeSH Browser
cri-2 protein, C elegans Chemical MeSH Browser