In Situ Nick-End Labeling [koncové značení zlomů DNA in situ]

topical
36
Terms

Tunel

 

In Situ Nick End Labeling
In Situ Nick End Labelling
In Situ Nick End-Labeling
In Situ Nick End-Labelling
In Situ Nick-End Labelling
Nick End-Labeling, In Situ
Nick End-Labelling, In Situ
Nick-End Labeling, In Situ
Nick-End Labelling, In Situ
TUNEL

Persistent link   https://www.medvik.cz/link/D020287
Definition

An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.

DUI
D020287 MeSH Browser
CUI
M0029936
Previous indexing
Apoptosis (1994-1998)
History note
1999
Public note
1999

E Analytical, Diagnostic and Therapeutic Techniques and Equipment
E01 Diagnosis 1 793
E02 Therapeutics 2 577
E05.393.128 Chemogenetics
E05.393.183 Chromosome Mapping 427
E05.393.220 Cloning, Molecular 407
E05.393.240 Cloning, Organism 98
E05.393.260 Contig Mapping 9
E05.393.281 Crosses, Genetic 96
E05.393.285 Cytogenetic Analysis 602
E05.393.290 DNA Fingerprinting 139
E05.393.300 DNA Footprinting 12
E05.393.335 Gene Targeting 28
E05.393.420 Genetic Engineering 520
E05.393.435 Genetic Testing 1 289
E05.393.442 Genotyping Techniques 161
E05.393.522 Molecular Epidemiology 148
E05.393.542 Molecular Typing 96
E05.393.560 Mutagenicity Tests 441
E05.393.667 Optogenetics 15
E05.393.673 Pedigree 550
E05.393.712 Restriction Mapping 65
E05.393.731 Reverse Genetics 4
E05.393.751 Sequence Alignment 301
E05.393.760 Sequence Analysis 136
E05.393.880 Viral Pseudotyping 1
E06 Dentistry 1 676