A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.

Annotation

do not confuse entry term GLIAL GROWTH FACTOR with GLIA MATURATION FACTOR

DUI

D020890 MeSH Browser

CUI

M0328212

Previous indexing

Nerve Tissue Proteins (1980-1999); Glycoproteins (1986-1999)

History note

2000; use NEUREGULIN-1 (NM) 1993-1999; for GLIAL GROWTH FACTOR use GLIA MATURATION FACTOR (NM) 1980-1999

Public note

2000; NEUREGULIN-1 was indexed under GLYCOPROTEINS 1993-1999; GLIAL GROWTH FACTOR was indexed under NERVE TISSUE PROTEINS 1980-1999