Ubiquitin [ubikvitin]
topical
93
- Terms
-
lidský ubikvitin
ubiquitin
-
APF-1
ATP-Dependent Proteolysis Factor 1
High Mobility Protein 20
HMG-20
Ubiquitin, Human
Persistent link
https://www.medvik.cz/link/D025801
Definition
A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These ubiquitinated proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
- Annotation
- UBIQUITINS is also available
- DUI
- D025801 MeSH Browser
- CUI
- M0369737
- Previous indexing
- Chromosomal Proteins, Non-Histone (1977-1984); Nucleoproteins (1966-1977); Peptides (1975-1980); Ubiquitins (1985-2001)
- History note
- 2002; use UBIQUITINS (1985-2001)
- Public note
- 2002; see UBIQUITINS (1985-2001)
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 1
- AG
- agonists 0
- AN
- analysis 5
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 11
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 10
- HI
- history 0
- IM
- immunology 3
- IP
- isolation & purification 0
- ME
- metabolism 43
- PK
- pharmacokinetics 0
- PD
- pharmacology 2
- PH
- physiology 14
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 2
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs