Epothilones [epothilony]

topical
9
Terms

epothilon

 

Epothilon
Epothilone

Persistent link   https://www.medvik.cz/link/D034261
Definition

A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).

DUI
D034261 MeSH Browser
CUI
M0405146
Previous indexing
Epoxy Compounds (1995-2002); Macrolides (1998-2002)
History note
2003
Public note
2003

Allowable subheadings

AD
administration & dosage 4
AE
adverse effects 2
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics 1
PD
pharmacology 2
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 4
TO
toxicity
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D02.540 Lactones 204
D02.540.576 Polyketides 12
D02.540.576.500 Macrolides 350
D02.540.576.500.250 Amphidinolides
D02.540.576.500.500 Amphotericin B 219
D02.540.576.500.750 Antimycin A 14
D02.540.576.500.875 Brefeldin A 11
D02.540.576.500.937 Bryostatins 2
D02.540.576.500.968 Candicidin
D02.540.576.500.984 Epothilones 9
D02.540.576.500.992 Erythromycin 187
D02.540.576.500.994 Fidaxomicin 22
D02.540.576.500.996 Filipin 2
D02.540.576.500.997 Ivermectin 81
D02.540.576.500.998 Josamycin 8
D02.540.576.500.999 Leucomycins 2
D03 Heterocyclic Compounds 189
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D09 Carbohydrates 723
D10 Lipids 2 524
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 034
D27 Chemical Actions and Uses 374

(S)-14-methoxyepothilone Chemical MeSH Browser

10,11-didehydroepothilone D Chemical MeSH Browser

10,14-dihydroxy-9,11,13,13-tetramethyl-2-(1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl)-5-(7-nitro-benzo(1,2,5)oxadiazol-4-yl)-1-oxa-5-aza-cyclohexadecane-12,16-dione Chemical MeSH Browser

12,13-cyclopropyl-epothilone B Chemical MeSH Browser

12,13-desoxyepothilone F Chemical MeSH Browser

15-aza-12,13-desoxyepothilone B Chemical MeSH Browser

26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B Chemical MeSH Browser

9,10-dehydroepothilone D Chemical MeSH Browser

AV-EPO-106 Chemical MeSH Browser

BMS 310705 Chemical MeSH Browser

BMS-748285 Chemical MeSH Browser

BMS-753493 Chemical MeSH Browser

C12,13-cyclopropylepothilone A Chemical MeSH Browser

C26-hydroxyepothilone D Chemical MeSH Browser

KOS-1584 Chemical MeSH Browser

cryptothilone 1 Chemical MeSH Browser

desoxyepothilone A Chemical MeSH Browser

desoxyepothilone B Chemical MeSH Browser

epothilone 490 Chemical MeSH Browser

epothilone A Chemical MeSH Browser

epothilone B Chemical MeSH Browser

epothilone C Chemical MeSH Browser

epothilone E Chemical MeSH Browser

epothilone F Chemical MeSH Browser

epothilone I Chemical MeSH Browser

epothilone K Chemical MeSH Browser

fludelone Chemical MeSH Browser

ixabepilone Chemical MeSH Browser

sagopilone Chemical MeSH Browser

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