An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.

Annotation

"V" in alphaV is the letter not the roman numeral

DUI

D039564 MeSH Browser

CUI

M0230139

Previous indexing

Antigens, CD (1994-2002)

History note

2003; use INTEGRIN ALPHAV (NM) 1994-2002

Public note

2003; INTEGRIN ALPHAV was indexed under ANTIGENS, CD 1994-2002