The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.

DUI

D040121

CUI

M0222872

Předchozí užití

Glycoproteins (1993-2002)

Historická pozn.

2003; use SEMAPHORIN 3A (NM) 1994-2002

Veřejná pozn.

2003; COLLAPSIN (now SEMAPHORIN 3A) was indexed under GLYCOPROTEINS 1993-2002