A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.

DUI

D040281 MeSH Prohlížeč

CUI

M0175703

RN

EC 2.7.10.1

Předchozí užití

Receptors, Growth Factor (1993-2002); Proto-Oncogene Proteins (1991-2002); Receptor Protein-Tyrosine Kinases (1991-2002)

Historická pozn.

2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002

Veřejná pozn.

2003; PROTO-ONCOGENE PROTEIN FLT (now VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1) was indexed under PROTO-ONCOGENE PROTEINS & RECEPTOR PROTEIN-TYROSINE KINASE 1991-2002