An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).

Annotation

entry terms PARAOXONASE-1, and PARAOXONASE-2 see SCR for organism specific terms

DUI

D043303 MeSH Browser

CUI

M0080022

Previous indexing

Esterases (1980-2003)

History note

2004; use ARYLDIALKYLPHOSPHATASE (NM) 1980 - 2003

Public note

2004; ARYLDIALKYLPHOSPHATASE was indexed under ESTERASES 1994-2003; PHOSPHORIC MONOESTER HYRDOLASES 1990-1993; PHOSPHOMONOESTERASES 1982-1989