Proteasome Endopeptidase Complex [proteasomový endopeptidasový komplex]

topical
96
Terms

20S proteazom
ingensin
multikatalytická proteinasa
multikatalytická proteináza
multikatalytické proteinázy
prosomy
proteasom
proteasomy
proteazom
proteazomový endopeptidázový komplex
proteazomy
prozom

 

20S Proteasome
Ingensin
Macropain
Macroxyproteinase
Multicatalytic Endopeptidase Complex
Multicatalytic Proteinase
Prosome
Proteasome

Persistent link   https://www.medvik.cz/link/D046988
Definition

A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.

DUI
D046988 MeSH Browser
CUI
M0140424
Previous indexing
Cysteine Endopeptidases (1986-2004); Multienzyme Complexes (1986-2004)
History note
2005; use PROTEASOME ENDOPEPTIDASE COMPLEX (NM) 1986-2004
Public note
2005; PROTEASOME ENDOPEPTIDASE COMPLEX was indexed under CYSTEINE ENDOPEPTIDASES & MULTIENZYME COMPLEXES 1986-2004

Combination

antagonists & inhibitors
Proteasome Inhibitors

Allowable subheadings

AD
administration & dosage 2
AE
adverse effects 2
AN
analysis 1
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 6
CL
classification
DF
deficiency
DE
drug effects 7
EC
economics
GE
genetics 10
HI
history
IM
immunology 5
IP
isolation & purification 1
ME
metabolism 52
PK
pharmacokinetics 1
PD
pharmacology 1
PH
physiology 10
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 5
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D05 Macromolecular Substances 103
D05.500 Multiprotein Complexes 65
D05.500.562 Multienzyme Complexes 40
D05.500.562.249 Electron Transport Complex I 44
D05.500.562.374 Electron Transport Complex IV 221
D05.500.562.405 Exosome Multienzyme Ribonuclease Complex 12
D05.500.562.444 Fatty Acid Synthase, Type II 1
D05.500.562.452 Glycine Decarboxylase Complex 1
D05.500.562.468 Ketoglutarate Dehydrogenase Complex 8
D05.500.562.484 Phosphoenolpyruvate Sugar Phosphotransferase System
D05.500.562.488 Photosynthetic Reaction Center Complex Proteins 14
D05.500.562.500 Proteasome Endopeptidase Complex 96
D05.500.562.625 Pyruvate Dehydrogenase Complex 12
D05.500.562.750 Succinate Cytochrome c Oxidoreductase 4
D05.500.562.875 Sucrase-Isomaltase Complex 1
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.277 Hydrolases 475
D08.811.277.656 Peptide Hydrolases 560
D08.811.277.656.074 Aspartic Acid Proteases 18
D08.811.277.656.149 ATP-Dependent Proteases 7
D08.811.277.656.224 Cathepsins 68
D08.811.277.656.262 Cysteine Proteases 12
D08.811.277.656.300 Endopeptidases 211
D08.811.277.656.350 Exopeptidases 4
D08.811.277.656.675 Metalloproteases 58
D08.811.277.656.837 Proprotein Convertases 91
D08.811.277.656.918 Proteasome Endopeptidase Complex 96
D08.811.277.656.959 Serine Proteases 21
D08.811.277.656.979 Viral Proteases 2
D08.811.600 Multienzyme Complexes 40
D08.811.600.075 Anthranilate Phosphoribosyltransferase 1
D08.811.600.085 Anthranilate Synthase 1
D08.811.600.250 Electron Transport Chain Complex Proteins 31
D08.811.600.283 Exosome Multienzyme Ribonuclease Complex 12
D08.811.600.354 Fatty Acid Synthase, Type II 1
D08.811.600.391 Glycine Decarboxylase Complex 1
D08.811.600.465 Ketoglutarate Dehydrogenase Complex 8
D08.811.600.620 Mi-2 Nucleosome Remodeling and Deacetylase Complex 2
D08.811.600.700 Phosphoenolpyruvate Sugar Phosphotransferase System
D08.811.600.710 Photosynthetic Reaction Center Complex Proteins 14
D08.811.600.715 Polyketide Synthases 6
D08.811.600.720 Prostaglandin-Endoperoxide Synthases 40
D08.811.600.730 Proteasome Endopeptidase Complex 96
D08.811.600.741 Pyruvate Dehydrogenase Complex 12
D08.811.600.795 Sin3 Histone Deacetylase and Corepressor Complex
D08.811.600.850 Sucrase-Isomaltase Complex 1
D08.811.600.896 Tryptophan Synthase 2
D08.811.600.948 Viral Replicase Complex Proteins

26S proteasome non-ATPase regulatory subunit 13 Chemical MeSH Browser

AT1G13060 protein, Arabidopsis Chemical MeSH Browser

ATP dependent 26S protease Chemical MeSH Browser

Blm10 protein, S cerevisiae Chemical MeSH Browser

ECPAS protein, human Chemical MeSH Browser

Ecm29 protein, S cerevisiae Chemical MeSH Browser

Ecpas protein, mouse Chemical MeSH Browser

Ki antigen Chemical MeSH Browser

LMP7 protein Chemical MeSH Browser

NAS6 protein, S cerevisiae Chemical MeSH Browser

PA28 protein, rat Chemical MeSH Browser

PA700 proteasome activator Chemical MeSH Browser

PRE2 protein, S cerevisiae Chemical MeSH Browser

PRE3 protein, S cerevisiae Chemical MeSH Browser

PRE4 protein, S cerevisiae Chemical MeSH Browser

PSA2 protein, mouse Chemical MeSH Browser

PSMA1 protein, human Chemical MeSH Browser

PSMA2 protein, human Chemical MeSH Browser

PSMA4 protein, human Chemical MeSH Browser

PSMA5 protein, human Chemical MeSH Browser

PSMA6 protein, human Chemical MeSH Browser

PSMA6 protein, mouse Chemical MeSH Browser

PSMA6 protein, rat Chemical MeSH Browser

PSMA7 protein, human Chemical MeSH Browser

PSMB1 protein, human Chemical MeSH Browser

PSMB10 protein, human Chemical MeSH Browser

PSMB11 protein, human Chemical MeSH Browser

PSMB2 protein, human Chemical MeSH Browser

PSMB2 protein, mouse Chemical MeSH Browser

PSMB4 protein, human Chemical MeSH Browser

PSMB4 protein, rat Chemical MeSH Browser

PSMB5 protein, human Chemical MeSH Browser

PSMB6 protein, human Chemical MeSH Browser

PSMB6 protein, rat Chemical MeSH Browser

PSMB7 protein, human Chemical MeSH Browser

PSMC2 protein, human Chemical MeSH Browser

PSMC3 protein, human Chemical MeSH Browser

PSMC4 protein, human Chemical MeSH Browser

PSMC5 protein, human Chemical MeSH Browser

PSMC6 protein, human Chemical MeSH Browser

PSMD1 protein, human Chemical MeSH Browser

PSMD10 protein, Danio rerio Chemical MeSH Browser

PSMD10 protein, human Chemical MeSH Browser

PSMD11 protein, human Chemical MeSH Browser

PSMD12 protein, human Chemical MeSH Browser

PSMD14 protein, human Chemical MeSH Browser

PSMD14 protein, mouse Chemical MeSH Browser

PSMD5 protein, human Chemical MeSH Browser

PSMD8 protein, human Chemical MeSH Browser

PSMD9 protein, human Chemical MeSH Browser

PSME1 protein, human Chemical MeSH Browser

PSME2 protein, human Chemical MeSH Browser

PSMF1 protein, human Chemical MeSH Browser

PUP2 protein, S cerevisiae Chemical MeSH Browser

Pre10 protein, S cerevisiae Chemical MeSH Browser

Pre6 protein, S cerevisiae Chemical MeSH Browser

Prosalpha4T1 protein, Drosophila Chemical MeSH Browser

Prosalpha4T2 protein, Drosophila Chemical MeSH Browser

Psma4 protein, mouse Chemical MeSH Browser

Psma8 protein, mouse Chemical MeSH Browser

Psmb10 protein, mouse Chemical MeSH Browser

Psmb11 protein, mouse Chemical MeSH Browser

Psmb5 protein, mouse Chemical MeSH Browser

Psmb5 protein, rat Chemical MeSH Browser

Psmc3 protein, mouse Chemical MeSH Browser

Psmc3 protein, rat Chemical MeSH Browser

Psmc5 protein, mouse Chemical MeSH Browser

Psmc5 protein, rat Chemical MeSH Browser

Psmd12 protein, mouse Chemical MeSH Browser

Psmd5 protein, mouse Chemical MeSH Browser

Psmd9 protein, mouse Chemical MeSH Browser

Psme1 protein, mouse Chemical MeSH Browser

Psme2 protein, mouse Chemical MeSH Browser

Psmf1 protein, mouse Chemical MeSH Browser

RPN-12 protein, C elegans Chemical MeSH Browser

RPN-6.1 protein, C elegans Chemical MeSH Browser

RPN1 protein, S cerevisiae Chemical MeSH Browser

RPN1 protein, human Chemical MeSH Browser

RPN10 protein, S cerevisiae Chemical MeSH Browser

RPN12 protein, S cerevisiae Chemical MeSH Browser

RPN13 protein, S cerevisiae Chemical MeSH Browser

RPN2 protein, S cerevisiae Chemical MeSH Browser

RPN2 protein, human Chemical MeSH Browser

RPN3 protein, S cerevisiae Chemical MeSH Browser

RPT-6 protein, C elegans Chemical MeSH Browser

RPT1 protein, S cerevisiae Chemical MeSH Browser

RPT4 protein, S cerevisiae Chemical MeSH Browser

RPT6 protein, S cerevisiae Chemical MeSH Browser

Rpn10 protein, rat Chemical MeSH Browser

Rpn14 protein, S cerevisiae Chemical MeSH Browser

Rpn5 protein, S cerevisiae Chemical MeSH Browser

Rpn7 protein, S cerevisiae Chemical MeSH Browser

Rpn8 protein, S cerevisiae Chemical MeSH Browser

Rpn9 protein, S cerevisiae Chemical MeSH Browser

Rpt3 protein, S pombe Chemical MeSH Browser

Rpt5 protein, Drosophila Chemical MeSH Browser

SCL1 protein, S cerevisiae Chemical MeSH Browser

SEM1 protein, S cerevisiae Chemical MeSH Browser

SEM1 protein, human Chemical MeSH Browser

proteasome 26S subunit, non-ATPase 6, human Chemical MeSH Browser

proteasome activator PA700 subunit p58, human Chemical MeSH Browser

proteasome subunit beta5t, mouse Chemical MeSH Browser

psmc3 protein, zebrafish Chemical MeSH Browser

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