Inteins [inteiny]

topical
1
Terms

Intervening Protein Sequence
Introns, Protein
Protein Introns

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Definition

The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.

DUI
D047668 MeSH Browser
CUI
M0458475
Previous indexing
Protein Splicing (1997-2004)
History note
2005
Public note
2005