Metabolic Detoxication, Phase II [II. fáze biotransformace]

topical
6
Terms

druhá fáze biotransformace
konjugační fáze biotransformace
metabolická detoxikace - II. fáze
metabolická detoxikace konjugační

 

Metabolic Detoxication, Conjugative
Metabolic Detoxification, Phase II
Phase II Detoxification

Persistent link   https://www.medvik.cz/link/D050217
Definition

The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.

DUI
D050217 MeSH Browser
CUI
M0473296
History note
2006
Public note
2006

Allowable subheadings

EH
ethnology 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G03 Metabolic Phenomena obsolete
G03.171 Biotransformation 794
G03.171.450 Inactivation, Metabolic 114
G03.171.450.500 Metabolic Detoxication, Phase I 7
G03.171.450.750 Metabolic Detoxication, Phase II 6
G03.787 Pharmacokinetics 750
G03.787.225 Biotransformation 794
G03.787.225.450 Inactivation, Metabolic 114
G03.787.225.450.500 Metabolic Detoxication, Phase I 7
G03.787.225.450.750 Metabolic Detoxication, Phase II 6
G07 Physiological Phenomena 176
G07.690 Pharmacological and Toxicological Phenomena 59
G07.690.725 Pharmacokinetics 750
G07.690.725.225 Biotransformation 794
G07.690.725.225.450 Inactivation, Metabolic 114
G07.690.725.225.450.500 Metabolic Detoxication, Phase I 7
G07.690.725.225.450.750 Metabolic Detoxication, Phase II 6

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