Squalene Monooxygenase [skvalenmonooxygenasa]
- Terms
-
skvalenmonooxygenáza
-
Squalene Epoxidase
Squalene Monooxygenase (2,3-Epoxidizing)
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
- DUI
- D050603 MeSH Browser
- CUI
- M0079002
- History note
- 2006(1980); use ETHERS, CYCLIC 1970-1979
- Public note
- 2006; SQUALENE MONOOXYGENASE was indexed under OXYGENASES 1981-2005 & ETHERS, CYCLIC 1970-1980
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SQLE protein, human Chemical MeSH Browser