Fanconi Anemia Complementation Group L Protein [protein FANCL]

topical
2
Terms

FANCL Protein
Fanconi Anemia Group L Complementing Protein
Fanconi Anemia Group L Protein
PHD Finger Protein 9
Ubiquitin Ligase Protein PHF9

Persistent link   https://www.medvik.cz/link/D052240
Definition

An E3 UBIQUITIN LIGASE that plays a key role in the DNA damage response pathway of FANCONI ANEMIA PROTEINS. It is associated with mono-ubiquitination of FANCD2 PROTEIN and the redistribution of FANCD2 to nuclear foci containing BRCA1 PROTEIN.

DUI
D052240 MeSH Browser
CUI
M0483809
RN
EC 2.3.2.27
History note
2006 (2003)
Public note
2006; FANCONI ANEMIA COMPLEMENTATION GROUP L PROTEIN was indexed under LIGASES 2003-2005

D Chemicals and Drugs
D08.811 Enzymes 1 547
D08.811.464 Ligases 33
D08.811.464.938.750 Ubiquitin-Protein Ligases 79
D08.811.464.938.750.092 Anaphase-Promoting Complex-Cyclosome 12
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins 29
D08.811.464.938.750.257 Nedd4 Ubiquitin Protein Ligases
D08.811.464.938.750.280 Polycomb Repressive Complex 1 6
D08.811.464.938.750.374 Proto-Oncogene Proteins c-cbl 5
D08.811.464.938.750.562 Proto-Oncogene Proteins c-mdm2 65
D08.811.464.938.750.656 Receptors, Autocrine Motility Factor 1
D08.811.464.938.750.750 SKP Cullin F-Box Protein Ligases 14
D12.776 Proteins 2 575
D12.776.313.125 BRCA1 Protein 101
D12.776.313.249 BRCA2 Protein 95
D12.776.313.968 Rad51 Recombinase 42