Von Hippel-Lindau Tumor Suppressor Protein [nádorový supresorový protein VHL]

topical
31
Terms

VHL protein
von Hippelova-Lindauova nemoc - nádorový supresorový protein
von Hippelův-Lindauův syndrom - nádorový supresorový protein

 

VHL Tumor Suppressor Protein

Persistent link   https://www.medvik.cz/link/D051794
Definition

A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.

DUI
D051794 MeSH Browser
CUI
M0481855
History note
2006 (1995)
Public note
2006; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN was indexed under TUMOR SUPPRESSOR PROTEINS 2002-2005, under UBIQUITIN-PROTEIN LIGASES 2004-2005, under LIGASES 2002-3003, under PROTEINS 1995-2001, & under NUCLEAR PROTEINS 1995

D Chemicals and Drugs
D08.811 Enzymes 1 557
D08.811.464 Ligases 33
D08.811.464.938.750 Ubiquitin-Protein Ligases 86
D08.811.464.938.750.092 Anaphase-Promoting Complex-Cyclosome 12
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins 37
D08.811.464.938.750.257 Nedd4 Ubiquitin Protein Ligases 1
D08.811.464.938.750.280 Polycomb Repressive Complex 1 6
D08.811.464.938.750.374 Proto-Oncogene Proteins c-cbl 6
D08.811.464.938.750.562 Proto-Oncogene Proteins c-mdm2 68
D08.811.464.938.750.656 Receptors, Autocrine Motility Factor 1
D08.811.464.938.750.703 Seven in Absentia Proteins
D08.811.464.938.750.750 SKP Cullin F-Box Protein Ligases 14
D08.811.464.938.750.766 TRIM21 Protein
D12.776 Proteins 2 596
D12.776.624 Neoplasm Proteins 418
D12.776.624.776 Tumor Suppressor Proteins 273
D12.776.624.776.021 DCC Receptor
D12.776.624.776.100 BRCA1 Protein 108
D12.776.624.776.101 BRCA2 Protein 102
D12.776.624.776.418 Cystatin M
D12.776.624.776.482 Deubiquitinating Enzyme CYLD 1
D12.776.624.776.523 Kangai-1 Protein 1
D12.776.624.776.546 Kisspeptins 8
D12.776.624.776.610 Neurofibromin 1 14
D12.776.624.776.612 Neurofibromin 2 3
D12.776.624.776.633 Patched Receptors
D12.776.624.776.654 Promyelocytic Leukemia Protein 4
D12.776.624.776.695 PTEN Phosphohydrolase 53
D12.776.624.776.745 Retinoblastoma Protein 52
D12.776.624.776.760 Smad4 Protein 7
D12.776.624.776.772 Tumor Suppressor Protein p14ARF 4
D12.776.624.776.775 Tumor Suppressor Protein p53 773
D12.776.624.776.820 Tumor Protein p73 6
D12.776.624.776.960 WT1 Proteins 30

VHL protein, human Chemical MeSH Browser

VHL protein, mouse Chemical MeSH Browser

VHLL protein, human Chemical MeSH Browser