Deubiquitinating Enzyme CYLD [deubikvitinizační enzym CYLD]
- Terms
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deubiquitinační enzym CYLD
protein CYLD
protein cylindromatózy
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CYLD Protein
Cylindromatosis Protein
Deubiquitinating Enzyme Cylindromatosis
A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.
- DUI
- D000074749 MeSH Browser
- CUI
- M000627388
- Previous indexing
- Tumor Suppressor Proteins (2001-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
CYLD protein, Drosophila Chemical MeSH Browser
CYLD protein, human Chemical MeSH Browser
CYLD protein, mouse Chemical MeSH Browser