kaspasa 2 [Caspase 2]

tematický
12
Termíny

kaspasa 2 - podjednotka p12
kaspasa 2 - podjednotka p13
kaspasa 2 - podjednotka p18
kaspasa-2
kaspáza 2
kaspáza 2, podjednotka p12
kaspáza 2, podjednotka p13
kaspáza 2, podjednotka p18
pro-kaspasa-2
prokaspasa-2
prokaspáza 2
proteasa ICH-1

 

Caspase 2 Subunit p12
Caspase 2 Subunit p13
Caspase 2 Subunit p18
Caspase-2
ICH-1 Protease
Pro-Caspase-2
Procaspase-2

Perzistentní odkaz   https://www.medvik.cz/link/D053143
Definice

Kaspáza s dlouhou prodoménou, která ve své prodoménové oblasti obsahuje doménu CARD. K aktivaci tohoto enzymu může dojít prostřednictvím interakce jeho domény CARD se signálními adaptorovými proteiny CARD. Kaspáza 2 hraje roli v procesu apoptózy tím, že štěpí a aktivuje efektorové prokaspázy. Díky vícenásobnému alternativnímu sestřihu jeho messenger RNA existuje několik izoforem tohoto proteinu.

A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

DUI
D053143 MeSH Prohlížeč
CUI
M0236588
Historická pozn.
2007(1994)
Veřejná pozn.
2007; CASPASE 2 was indexed under CASPASES 1994-2006

D Chemikálie a léčiva
D08.811 enzymy 1 551
D08.811.277 hydrolasy 475
D08.811.277.656 proteasy 560
D08.811.277.656.262 cysteinové proteasy 12
D08.811.277.656.262.500 cysteinové endopeptidasy 44
D08.811.277.656.262.500.126 kaspasy 158
D08.811.277.656.262.500.126.550 iniciační kaspasy 3
D08.811.277.656.262.500.126.550.100 kaspasa 1 16
D08.811.277.656.262.500.126.550.200 kaspasa 2 12
D08.811.277.656.262.500.126.550.800 kaspasa 8 20
D08.811.277.656.262.500.126.550.900 kaspasa 9 24
D08.811.277.656.262.500.126.550.910 kaspasa 10 2
D08.811.277.656.262.500.126.550.920 kaspasa 12 3
D08.811.277.656.300 endopeptidasy 211
D08.811.277.656.300.200 cysteinové endopeptidasy 44
D08.811.277.656.300.200.126 kaspasy 158
D08.811.277.656.300.200.126.550 iniciační kaspasy 3
D08.811.277.656.300.200.126.550.100 kaspasa 1 16
D08.811.277.656.300.200.126.550.200 kaspasa 2 12
D08.811.277.656.300.200.126.550.800 kaspasa 8 20
D08.811.277.656.300.200.126.550.900 kaspasa 9 24
D08.811.277.656.300.200.126.550.910 kaspasa 10 2
D08.811.277.656.300.200.126.550.920 kaspasa 12 3
D12.776 proteiny 2 581
D12.776.476.075.405 kaspasy 158
D12.776.476.075.405.550 iniciační kaspasy 3
D12.776.476.075.405.550.100 kaspasa 1 16
D12.776.476.075.405.550.200 kaspasa 2 12
D12.776.476.075.405.550.800 kaspasa 8 20
D12.776.476.075.405.550.900 kaspasa 9 24
D12.776.476.075.405.550.910 kaspasa 10 2
D12.776.476.075.405.550.920 kaspasa 12 3

CASP2 protein, human Chemical MeSH Prohlížeč

Casp2 protein, mouse Chemical MeSH Prohlížeč