Receptors, Death Domain [receptory domény smrti]
- Terms
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receptory smrtící domény
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Death Domain Receptors
Death Receptor
Death Receptors
Receptors, Death Domain Family
Receptors, DR Family
A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES.
- DUI
- D053218 MeSH Browser
- CUI
- M0492026
- History note
- 2007
- Public note
- 2007
Allowable subheadings
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- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
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- GE
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- IM
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- IP
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- ME
- metabolism 3
- PH
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- RE
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- TU
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