apoptozómy [Apoptosomes]

tematický
2
Termíny

apoptozóm

 

Apoptosomal Protein Complex
Apoptosome

Perzistentní odkaz   https://www.medvik.cz/link/D053478
Definice

Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.

DUI
D053478 MeSH Prohlížeč
CUI
M0493498
Předchozí užití
Apoptosis (1999-2006)
Historická pozn.
2007
Veřejná pozn.
2007