presenilin-1 [Presenilin-1]

tematický
11
Termíny

presenilin 1
protein S182

 

Presenilin 1
S182 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D053764
Definice

Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. PSEN1 mutations cause early-onset ALZHEIMER DISEASE type 3 that may occur as early as 30 years of age in humans.

DUI
D053764 MeSH Prohlížeč
CUI
M0248671
Předchozí užití
Alzheimer Disease (1995-2006); Membrane Proteins (1995-2006)
Historická pozn.
2007
Veřejná pozn.
2007; was indexed under MEMBRANE PROTEINS 1995-2006

LATS1-PSEN1 fusion protein, human Chemical MeSH Prohlížeč

PSEN1 protein, human Chemical MeSH Prohlížeč

Psen1 protein, rat Chemical MeSH Prohlížeč

Psen1 protein, zebrafish Chemical MeSH Prohlížeč

presenilin 1, mouse Chemical MeSH Prohlížeč