Sirtuin 1 [sirtuin 1]

topical
29
Terms

Sirt1

 

Silent Mating Type Information Regulation 2 Homolog 1
Sirt1

Persistent link   https://www.medvik.cz/link/D056564
Definition

A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.

DUI
D056564 MeSH Browser
CUI
M0527779
Previous indexing
Histone Deacetylases (2002-2006); Sirtuins (2007-2009)
History note
2010
Public note
2010

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 1
AI
antagonists & inhibitors 5
BI
biosynthesis 1
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 7
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 19
PK
pharmacokinetics 1
PD
pharmacology 2
PH
physiology 3
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.277 Hydrolases 475
D08.811.277.087 Amidohydrolases 45
D08.811.277.087.520 Histone Deacetylases 69
D08.811.277.087.520.200 Group III Histone Deacetylases
D08.811.277.087.520.200.650 Sirtuins 20
D08.811.277.087.520.200.650.100 Sirtuin 1 29
D08.811.277.087.520.200.650.200 Sirtuin 2 3
D08.811.277.087.520.200.650.600 Sirtuin 3 5
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.900 Sirtuins 20
D12.776.476.900.100 Sirtuin 1 29
D12.776.476.900.200 Sirtuin 2 3
D12.776.476.900.600 Sirtuin 3 5

SIRT1 protein, human Chemical MeSH Browser

Sirt1 protein, mouse Chemical MeSH Browser

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