Polycomb Repressive Complex 1 [PRC1]
topical
6
- Terms
-
represivní komplex Polycomb 1
Persistent link
https://www.medvik.cz/link/D063150
Definition
A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION.
- DUI
- D063150 MeSH Browser
- CUI
- M0499462
- RN
- EC 2.3.2.27
- Previous indexing
- Repressor Proteins (1998-2012); Transcription Factors (1997)
- History note
- 2013
- Public note
- 2013
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 1
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 2
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.464.938.750.257
Nedd4 Ubiquitin Protein Ligases
D08.811.464.938.750.782
Tripartite Motif-Containing Protein 28