Autoři prezentují kazuistiku pacienta, který v domácích podmínkách provedl autokastraci levého varlete s nutností následné operační revize. Dále popisují průběh hospitalizace s překladem na psychiatrické pracoviště.
The authors present a case report of a patient who underwent a self-orchiectomy of his left testicle at home with the need of a subsequent surgical revision. Afterwards the authors describe the procedure of hospitalization with a following transfer to a psychiatric department.
Autoři prezentují kazuistiku pacienta, který v domácích podmínkách provedl autokastraci levého varlete s nutností následné operační revize. Dále popisují průběh hospitalizace s překladem na psychiatrické pracoviště.
The authors present a case report of a patient who underwent a self-orchiectomy of his left testicle at home with the need of a subsequentsurgical revision. Afterwards the authors describe the procedure of hospitalization with a following transfer to a psychiatric department.
V naší kazuistice popisujeme případ spontánní ruptury angiomyolipomu s krvácením do retroperitonea. U 33leté pacientky se spontánně vzniklým krvácením z tumoru levé ledviny do retroperitinea došlo k progresi anemie s nutností operační revize s provedením levostranné nefrektomie.
We present a case report of spontaneous rupture of an angiomyolipoma with bleeding into the retroperitoneum. A hirty three year-old woman with spontaneous rupture of an angiomyolipoma presented with progressive anemia. Bleeding into the retroperitoneum due to sponaneus rupture of an angiomyolipoma was diagnosed. This situation required surgical revision and left-sided nephrectomy.
- Klíčová slova
- Wunderlichův syndrom,
- MeSH
- angiomyolipom * diagnostické zobrazování komplikace patologie MeSH
- dospělí MeSH
- hemoperitoneum etiologie terapie MeSH
- lidé MeSH
- nádory ledvin komplikace MeSH
- nefrektomie MeSH
- retroperitoneální prostor chirurgie MeSH
- tuberózní skleróza farmakoterapie komplikace MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
AIMS AND OBJECTIVES: To establish the availability of High Efficiency Particulate Air (HEPA)- and nonHEPA-filtered rooms in eastern European transplant centres and to investigate the impact on incidence of pneumonia and mortality after haematopoietic stem cell transplantation (HSCT). BACKGROUND: Barrier nursing in HEPA-filtered rooms is generally recommended for patients undergoing HSCT. There are only limited data on the availability of HEPA-filtered rooms and the impact on incidence of pneumonia and mortality. DESIGN: A prospective, observational, international study. METHODS: Monitoring cards were distributed within the East Forum EBMT-Nurses Group cooperating centres, and 689 consecutive patients were registered in 1/2010-6/2012. Patients were monitored for 100 days post-transplant. RESULTS: In patients undergoing autologous HSCT, pneumonia developed in 14/400 (3·5%) and was the cause of death in 2/14 (14%) of patients. There was no significant difference in mortality between HEPA-filtered and nonHEPA-filtered groups (4·5% vs. 4·9%, respectively). 239/400 (59%) transplantations were performed in single-bed rooms [190/239 (79%) HEPA-filtered] and 161 (41%) in two-bed rooms [28/161 (17%) HEPA-filtered]. In allogeneic transplantation, pneumonia developed in 24/289 (8·3%) and was the cause of death in 11/24 (45%) of patients. There was no significant difference in mortality between HEPA-filtered and non-HEPA-filtered groups (14% vs. 17%, respectively). 281/289 (97%) of allogeneic transplantations were performed in single-bed rooms [254/281 (90%) HEPA-filtered], and pneumonia was more frequent in patients on corticosteroids and in rooms without HEPA. CONCLUSION: The incidence of pneumonia in the autologous transplantation setting is low. More pneumonia was observed in the allogeneic HSCT group, especially in patients on corticosteroids. There was a trend towards a lower incidence of pneumonia in allogeneic HSCT patients treated in HEPA-filtered rooms. RELEVANCE TO CLINICAL PRACTICE: Autologous HSCT transplantation may safely be performed without HEPA filtration. HEPA filtration might be preferable in patients undergoing allogeneic transplantation.
- MeSH
- dospělí MeSH
- incidence MeSH
- izolace pacientů * MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- pneumonie epidemiologie etiologie ošetřování prevence a kontrola MeSH
- pokoje pro pacienty * MeSH
- prospektivní studie MeSH
- senioři MeSH
- transplantace hematopoetických kmenových buněk * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Evropa MeSH
- Publikační typ
- abstrakt z konference MeSH
PURPOSE: Oral mucositis (OM) still represents a significant complication of hematopoietic stem cell transplantations (HSCT). Observational studies focusing on risk factor definitions are still warranted. METHOD: A total of 126 patients participated in this observational study after autologous HSCT with the BEAM and HD-l-PAM 200mg/m(2) conditioning regimens. Basic clinical and laboratory variables and their impact on OM were assessed. RESULTS: Age, gender, body mass index, and baseline absolute neutrophil counts were not shown to have any negative impact on OM development. The multivariate analysis revealed oral cryotherapy non-provision as being the most significant predictor for OM incidence (p < 0.0001), followed by BEAM conditioning regimen (p = 0.007), OM in a patient's history (p = 0.002) and lower number of days since the last chemotherapy (p = 0.025). The cryotherapy was remarkably effective both in the single high-dose melphalan 200mg/m(2) conditioning regimen (18% OM in cryotherapy vs. 68% without it, p<0.0001) and in the multidrug BEAM (melphalan 140mg/m(2)) regimen (38% vs. 86%, p=0.006). CONCLUSION: Oral cryotherapy should be implemented into supportive care management in patients treated with high-dose melphalan short-infusion chemotherapy. Large and well-designed randomized trials are necessary to obtain more significant and reliable results and understanding regarding OM risk factors.
- MeSH
- autologní transplantace MeSH
- cytarabin aplikace a dávkování škodlivé účinky MeSH
- dospělí MeSH
- etoposid aplikace a dávkování škodlivé účinky MeSH
- karmustin aplikace a dávkování škodlivé účinky MeSH
- kryoterapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- melfalan aplikace a dávkování škodlivé účinky MeSH
- mladiství MeSH
- mladý dospělý MeSH
- příprava pacienta k transplantaci škodlivé účinky metody MeSH
- prospektivní studie MeSH
- protokoly antitumorózní kombinované chemoterapie aplikace a dávkování škodlivé účinky terapeutické užití MeSH
- rizikové faktory MeSH
- rozvrh dávkování léků MeSH
- senioři MeSH
- stomatitida etiologie prevence a kontrola MeSH
- transplantace hematopoetických kmenových buněk škodlivé účinky MeSH
- výsledek terapie MeSH
- vztah mezi dávkou a účinkem léčiva MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- multicentrická studie MeSH
- Klíčová slova
- dutina ústní,
- MeSH
- farmakoterapie MeSH
- hygiena MeSH
- Klíčová slova
- ošetřovatelská péče, transplantace kmenových buněk krvetvorby, výživa pacienta,
- MeSH
- leukemie MeSH
