First edition 2 svazky (xxi, 1723, liii stran) : ilustrace, tabulky ; 29 cm
- MeSH
- Surgical Procedures, Operative MeSH
- Tissue and Organ Harvesting MeSH
- Organ Transplantation * MeSH
- Publication type
- Textbook MeSH
- Conspectus
- Patologie. Klinická medicína
- NML Fields
- transplantologie
- NML Publication type
- kolektivní monografie
Pediatric clinics of North America, ISSN 0031-3955 vol. 50, no. 6, December 2003
xvi, 1233-1630 s. : il., tab. ; 24 cm
- MeSH
- Child MeSH
- Immunization MeSH
- Immunosuppressive Agents MeSH
- Organ Transplantation MeSH
- Transplantation Immunology MeSH
- Check Tag
- Child MeSH
- Conspectus
- Pediatrie
- NML Fields
- pediatrie
- transplantologie
Right-sided BSCA provides for satisfactory pulmonary arterial growth in infants and children with complex congenital heart defects, and it could enhance the growth of a small right pulmonary artery. The growth of the left pulmonary artery, particularly in younger patients, needs close attention to confirm the safe role of BSCA in long-term palliation.
- MeSH
- Anastomosis, Surgical methods MeSH
- Pulmonary Artery surgery growth & development MeSH
- Child MeSH
- Infant MeSH
- Humans MeSH
- Linear Models MeSH
- Infant, Newborn MeSH
- Palliative Care MeSH
- Child, Preschool MeSH
- Vena Cava, Superior surgery MeSH
- Heart Defects, Congenital surgery MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Male MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
- Female MeSH
BACKGROUND: It is common practice to interrupt all alternative sources of pulmonary blood flow ("competitive flow") at the time of a bidirectional superior cavopulmonary anastomosis (BCPA), although the merits of this have not been systematically studied. METHODS AND RESULTS: We reviewed the early and medium-term clinical and hemodynamic findings in 108 consecutive patients 3 weeks to 25 years old (median, 1.9 years) undergoing BCPA at one of three institutions. Preoperatively, pulmonary blood flow was dependent on antegrade ventricular flow (n = 50), systemic-to-pulmonary shunts (n = 33), or mixed sources (n = 25). Postoperatively, competitive sources of pulmonary blood flow were left patent in 43 of 108 patients (40%). There were four early (3.7%) and four late deaths, none related to persistence of competitive flow. After BCPA, patients with competitive flow had significantly higher systemic oxygen saturations at 1 hour (85% versus 79%), 24 hours (84% versus 78%), and at hospital discharge (84% versus 78%) and required a shorter period of artificial ventilation (median, 9 versus 24 hours) and intensive care (median, 2 versus 4 days). Oxygen saturations at late follow-up (median, 2.8 years; range, 1 to 7) did not differ (83% versus 82%). No patient developed pulmonary arteriovenous malformations. CONCLUSIONS: Competitive flow is well tolerated in the short and medium term after BCPA, and early postoperative systemic oxygen saturations are improved. The long-term influence of competitive flow on pulmonary arterial growth, arteriovenous malformation development, and ventricular function warrants investigation.
- MeSH
- Heart Bypass, Right methods mortality MeSH
- Child MeSH
- Adult MeSH
- Hemodynamics MeSH
- Infant MeSH
- Oxygen blood MeSH
- Humans MeSH
- Adolescent MeSH
- Follow-Up Studies MeSH
- Infant, Newborn MeSH
- Palliative Care MeSH
- Pulmonary Circulation MeSH
- Postoperative Complications MeSH
- Postoperative Period MeSH
- Child, Preschool MeSH
- Retrospective Studies MeSH
- Aging physiology MeSH
- Treatment Outcome MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Infant MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
- Female MeSH