Příručka se zaměřuje na praktická cvičení z terapie uměním, kterou lze využít v terapii úzkosti, deprese nebo PTSD. Určeno široké veřejnosti.; Kniha obsahuje 75 art terapeutických aktivit pro zvládání poruch nálady a osobnosti. Každé cvičení obsahuje vysvětlení jeho účelu a možných výsledků spolu s řadou zasvěcených otázek k dané aktivitě. Autorka používá výtvarné umění jako nástroj k odstranění úzkostí, posttraumatických stresových poruch a objevení skrytých ozdravných schopností. Její arteterapeutické techniky propojují člověka s jeho podvědomím a používáním vlastní intuice k zvýšení sebevědomí, lepšímu rozhodování se a účelnějšího způsobu života. Naučte se základům různých uměleckých technik médií, jako jsou kresba, malba a sochařství a současně zlepšete svoje psychické zdraví. K zvládnutí všech cvičení nejsou nutné žádné předchozí umělecké zkušenosti ani zvláštní nadání.

• MeSH
• Art Therapy MeSH
• Depression MeSH
• Cognitive Behavioral Therapy MeSH
• Stress Disorders, Post-Traumatic MeSH
• Self Medication MeSH
• Anxiety MeSH
• Publication type
• Popular Work MeSH
• Handbook MeSH

• Conspectus
• Fyzioterapie. Psychoterapie. Alternativní lékařství
• NML Fields
• psychoterapie
• zdravotní výchova

OBJECTIVE: To analyze the relationship among the professional role (student or professor), geographic location, and mental health in the university community after the COVID-19 pandemic. METHODS: . Quantitative cross-sectional study conducted at universities in Spain, Germany, and the Czech Republic. Non-probability convenience sampling was used, obtaining a sample of 449 participants (372 students and 77 professors). Mental health was assessed using the Scale for Mood Evaluation (EVEA), measuring sadness-depression, anxiety, anger-hostility, and happiness. RESULTS: Significant differences were found between students and professors, with students reporting higher levels of sadness-depression (3.8 vs. 2.4; p<0.001), anxiety (4.6 vs. 2.9; p<0.001), and anger-hostility (3.4 vs. 2.5; p<0.01). Professors showed higher levels of happiness (6.7 vs. 5.4; p<0.001). In addition, differences among countries were observed: participants from Spain showed higher levels of sadness-depression and anxiety compared to Germany and the Czech Republic. CONCLUSION: University students have greater emotional vulnerability than professors, highlighting the need for differentiated psy-chosocial support strategies in the academic setting.

• MeSH
• Faculty * psychology   statistics & numerical data   MeSH
• COVID-19 * psychology   epidemiology   MeSH
• Depression epidemiology   MeSH
• Adult MeSH
• Mental Health * MeSH
• Humans MeSH
• Young Adult MeSH
• Cross-Sectional Studies MeSH
• Cross-Cultural Comparison MeSH
• Happiness MeSH
• Students * psychology   statistics & numerical data   MeSH
• Universities MeSH
• Anxiety epidemiology   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH
• Germany MeSH
• Spain MeSH

• Keywords
• Gapulsid,
• MeSH
• Benzamides * therapeutic use   MeSH
• Depression complications   MeSH
• Dyspepsia drug therapy   psychology   MeSH
• Escitalopram adverse effects   therapeutic use   MeSH
• Drug Therapy, Combination methods   MeSH
• Humans MeSH
• Selective Serotonin Reuptake Inhibitors * therapeutic use   MeSH
• Aged MeSH
• Anxiety complications   MeSH
• Check Tag
• Humans MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

PURPOSE: Epilepsy in children is often associated with impaired quality of life, lower academic achievement, and reduced academic self-concept, as well as an increased risk of depression and anxiety. This study aims to evaluate the possible impact of comorbidities, such as learning disabilities (LD) and attention deficit hyperactivity disorder (ADHD), on these variables. METHODS: A total of 104 children with epilepsy (CWE) aged 8-15 years, attending mainstream schools, participated in the study. Of these, 45 were diagnosed with LD and/or ADHD. Participants completed the CHEQOL-25 questionnaire to assess quality of life (QoL), the SPAS questionnaire to evaluate academic self-concept, as well as inventories measuring depressive and anxiety symptoms. The data were analyzed to identify differences between subgroups with and without LD/ADHD using a two-sample t-test. Additionally, correlation analysis was conducted to identify other relevant variables influencing QoL, academic self-concept, and depressive and anxiety symptoms. RESULTS: QoL and academic self-concept were significantly poorer in CWE with LD/ADHD compared to those without comorbidities. QoL showed statistically significant associations with depressive and anxiety symptoms, and academic self-concept. While depressive symptoms levels in CWE without comorbidities align with those in the general population, CWE with LD/ADHD showed an increased association with depressive symptoms. Although anxiety symptoms were relatively strongly associated with depressive symptoms, their prevalence remains broadly comparable to that of children without epilepsy, regardless of the presence of LD/ADHD. CONCLUSION: CWE with LD/ADHD and their families may benefit from focused attention, including targeted counseling and therapeutic interventions. However, specific interventional studies are recommended, based on child-specific findings.

• MeSH
• Depression epidemiology   psychology   MeSH
• Child MeSH
• Mental Health * MeSH
• Epilepsy * psychology   epidemiology   complications   MeSH
• Attention Deficit Disorder with Hyperactivity epidemiology   psychology   MeSH
• Comorbidity MeSH
• Quality of Life * psychology   MeSH
• Humans MeSH
• Adolescent MeSH
• Learning Disabilities * epidemiology   psychology   MeSH
• Surveys and Questionnaires MeSH
• Self Concept * MeSH
• Anxiety epidemiology   psychology   MeSH
• Check Tag
• Child MeSH
• Humans MeSH
• Adolescent MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH

Text představí ketaminem asistovanou psychoterapii (KAP) jako novou léčebnou modalitu v psychiatrii pro široké diagnostické spektrum. Tato metoda má odlišné charakteristiky i indikace od použití esketaminu či racemického ketaminu v off-label use u deprese. Je unikátní kombinací farmakologického i psychoterapeutického přístupu tím, že aktivně využívá změněný stav vědomí vyvolaný ketaminem k zásadní akceleraci a prohloubení psychoterapeutického procesu. Podkladem této akcelerace je indukce neuroplastického procesu, zvýšená schopnost učení, a tím pádem efektivnější psychoterapie. Metoda částečně navazuje jednak na objev rychlého antidepresivního a anxiolytického účinku ketaminu z přelomu tisíciletí, jednak na metodiku psychedelické psychoterapie 50. a 60. let 20. století. V současné době se rychle rozvíjí především v USA; v ČR implementuje tento model do zdravotní péče Psyon – Psychedelická klinika, ale v poslední době vznikají i další takto specializovaná pracoviště. Text je krátkým přehledem využití ketaminu v psychiatrii a souhrnem dosavadního výzkumu o použití ketaminu v psychoterapii, představí východiska KAP a odliší KAP od jiných přístupů práce s ketaminem.

The text introduces Ketamine-Assisted Psychotherapy (KAP) as a new therapeutic modality in psychiatry for a broad diagnostic range. This method has distinct characteristics and indications compared to the use of esketamine or racemic ketamine off-label for depression. KAP uniquely combines pharmacological and psychotherapeutic approaches by actively utilizing the altered state of consciousness induced by ketamine to significantly accelerate and deepen the psychotherapeutic process. The foundation of this acceleration lies in the induction of neuroplastic processes, enhanced learning capacity, and thereby more effective psychotherapy. The method partially builds on the discovery of ketamine's rapid antidepressant and anxiolytic effects from the turn of the millennium, as well as on the methodology of psychedelic psychotherapy from the 1950s and 1960s. Currently, it is rapidly developing, especially in the United States. In the Czech Republic, this model is being implemented into healthcare by Psyon – Psychedelic Clinic, and recently, other specialized centers have also emerged. The text is a brief overview of the use of ketamine in psychiatry and a summary of the current research on the application of ketamine in psychotherapy. It introduces the principles of KAP and distinguishes KAP from other approaches to working with ketamine.

• MeSH
• Depression drug therapy   therapy   MeSH
• Mental Disorders drug therapy   classification   therapy   MeSH
• Hallucinogens pharmacology   therapeutic use   MeSH
• Ketamine * pharmacology   therapeutic use   MeSH
• Combined Modality Therapy methods   MeSH
• Humans MeSH
• Obsessive-Compulsive Disorder drug therapy   therapy   MeSH
• Feeding and Eating Disorders drug therapy   therapy   MeSH
• Psychotherapy * methods   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH
• Review MeSH

• Keywords
• psychiatrizace,
• MeSH
• Depression epidemiology   etiology   MeSH
• Mental Disorders * epidemiology   etiology   MeSH
• Mental Health MeSH
• Epidemiologic Methods * MeSH
• Clinical Studies as Topic MeSH
• Humans MeSH
• Meta-Analysis as Topic MeSH
• Adolescent MeSH
• Check Tag
• Humans MeSH
• Adolescent MeSH
• Publication type
• Comment MeSH

OBJECTIVES: Medical students experience worse psychological well-being than the general population. Social determinants of health (SDOH) relate to conditions in which people live, work, and age and significantly influence mental health. This study examines the association between depressive symptoms and SDOH in medical students from four countries: Czechia, Iran, Kenya, and Venezuela. METHODS: An online cross-sectional survey was conducted in the spring of 2022. The questionnaire focused on depressive symptoms (using a validated psychiatric scale DASS-21 to assess mental health) and various SDOHs. RESULTS: A total of 2,033 medical students participated in the survey, with a median age of 23.0 years; 64.8% were females; 60.8% of respondents had some degree of depressive symptoms (mild-to-moderate 32.5%, severe-to-extremely severe 28.3%). Several SDOHs, such as low engagement in social life, low personal funds, and low social class, were strongly associated with severe-to-extremely severe depressive symptoms (p < 0.001), and the associations differed among countries. The prevalence of severe-to-extremely severe depressive symptoms varied significantly across the four countries, with Iran having the highest prevalence (OR = 2.1 compared to Czechia), followed by Czechia (OR = 1, reference value), Kenya (OR = 0.9), and Venezuela (OR = 0.6). CONCLUSION: The study demonstrates the high prevalence of depressive symptoms among medical students from four global regions and the significant association with specific SDOH. Notably, the variation in prevalence across countries and differential relationships with SDOH underscore the importance of considering transcultural factors in research and management to improve mental health among medical students.

• MeSH
• Depression * epidemiology   MeSH
• Adult MeSH
• Humans MeSH
• Young Adult MeSH
• Prevalence MeSH
• Cross-Sectional Studies MeSH
• Surveys and Questionnaires MeSH
• Social Determinants of Health * statistics & numerical data   MeSH
• Students, Medical * psychology   statistics & numerical data   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH
• Iran MeSH
• Kenya MeSH
• Venezuela MeSH

Depression affects hundreds of millions globally, and in 2019, esketamine, an S-enantiomer of ketamine, was approved for treatment-resistant depression (TRD). While effective, esketamine carries risks, including abuse potential and adverse effects even at low doses. As a result, ketamine's metabolite, (2R,6R)-hydroxynorketamine ((2R,6R)-HNK), has garnered attention for its potential antidepressant effects without these drawbacks. This selective review evaluates preclinical behavioral evidence for (2R,6R)-HNK's antidepressant properties, focusing on rodent studies that used established depression models. Results showed that (2R,6R)-HNK reduced behavioral despair, anhedonia, anxiety, and social avoidance in both stressed and non-stressed rodents. Antidepressant effects were observed at doses between 5 and 125 mg/kg, with rapid onset (30 min) and long-lasting effects (up to 21 days). However, some studies failed to demonstrate significant antidepressant effects at doses below 40 mg/kg, often in models with pre-induced depression. No significant adverse effects were reported, but data on side effects were limited. In conclusion, (2R,6R)-HNK shows promise as a next-generation antidepressant. However, further research is needed to fully understand its long-term safety and mechanisms, and to determine its advantages over existing treatments like esketamine, particularly for TRD patients.

• MeSH
• Antidepressive Agents * pharmacology   therapeutic use   adverse effects   MeSH
• Behavior, Animal drug effects   MeSH
• Depression * drug therapy   psychology   MeSH
• Ketamine * analogs & derivatives   pharmacology   therapeutic use   adverse effects   MeSH
• Humans MeSH
• Disease Models, Animal MeSH
• Drug Evaluation, Preclinical MeSH
• Animals MeSH
• Check Tag
• Humans MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Review MeSH

BACKGROUND: Psychological distress is recognized as an independent risk factor for cardiovascular diseases (CVDs), contributing to increased morbidity and mortality. While eHealth is increasingly used to deliver psychological interventions, their effectiveness for patients with CVDs remains unclear. OBJECTIVE: This meta-analysis aimed to evaluate the effects of eHealth psychological interventions for patients with CVDs. METHODS: Eligible studies were retrieved from 5 databases (Embase, Medline, PubMed, CINAHL, and Cochrane Library), covering the period from database inception to December 2024. Randomized controlled trials (RCTs) investigating the effect of evidence-based psychological eHealth interventions to improve psychosocial well-being and cardiovascular outcomes for people with CVDs were included. The Cochrane Risk of Bias tool (version 2) was used to judge the methodological quality of reviewed studies. RevMan (version 5.3) was used for meta-analysis. RESULTS: A total of 12 RCTs, comprising 2319 participants from 10 countries, were included in the review. The results demonstrated significant alleviation of depressive symptoms for patients receiving psychological eHealth intervention compared to controls (number of paper included in that particular analysis, n=7; standardized mean difference=-0.30, 95% CI -0.47 to -0.14; I2=57%; P<.001). More specifically, in 6 trials where internet-based cognitive behavioral therapy was delivered, a significant alleviation of depressive symptoms was achieved (standardized mean difference=-0.39, 95% CI -0.56 to -0.21; I2=53%; P<.001). There was no significant change in anxiety or quality of life. Synthesis without meta-analysis regarding stress, adverse events, and cardiovascular events showed inconclusive findings. CONCLUSIONS: Psychological eHealth interventions, particularly internet-based cognitive behavioral therapy, can significantly reduce depressive symptoms among patients with CVDs. A multidisciplinary approach is crucial for comprehensively improving psychological and cardiovascular outcomes. Future studies should explore integrating persuasive design features into eHealth and involving mental health professionals for intervention delivery. TRIAL REGISTRATION: PROSPERO CRD42023452276; https://www.crd.york.ac.uk/PROSPERO/view/CRD42023452276.

• MeSH
• Depression therapy   MeSH
• Cardiovascular Diseases * psychology   therapy   MeSH
• Cognitive Behavioral Therapy MeSH
• Humans MeSH
• Randomized Controlled Trials as Topic MeSH
• Telemedicine * MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH
• Meta-Analysis MeSH
• Review MeSH
• Systematic Review MeSH

University students frequently encounter stress and anxiety, impacting their autonomic nervous system and mental health. Rhythmic photic stimulation (RPS) at various frequencies is considered a potential intervention for anxiety and depression, but its effectiveness is not fully understood. This research aimed to assess the impact of RPS at theta (6 Hz), alpha (10 Hz), and beta (25 Hz) frequencies on autonomic nervous system regulation in university students, comparing the effects between those with and without depression symptoms. Conducted at a southern Taiwan university, this quasi-experimental study involved RPS interventions at specified frequencies, with pre and post assessments of heartbeat, blood pressure, and heart rate variability. Among 62 participants (average age 20.29±0.61), those without depression showed a notable blood pressure reduction following theta-frequency RPS compared to other frequencies (p<0.05). A similar pattern was observed when comparing non-depressed and depressed participants after theta-RPS, with depressed individuals experiencing an increase in sympathetic activity (p<0.05). RPS, particularly at theta frequency, can significantly influence the autonomic nervous system, suggesting a potential for reducing anxiety-related physiological markers in university students. Further verification with a larger and longitudinal study is warranted. Key words Binaural beat, Rhythmical photic stimulation, Autonomic nervous system, University student.

• MeSH
• Autonomic Nervous System * physiology   MeSH
• Depression physiopathology   psychology   MeSH
• Blood Pressure physiology   MeSH
• Humans MeSH
• Young Adult MeSH
• Heart Rate * physiology   MeSH
• Students * psychology   MeSH
• Photic Stimulation * methods   MeSH
• Universities MeSH
• Anxiety physiopathology   MeSH
• Check Tag
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH
• Publication type
• Journal Article MeSH