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MeSH: Disorders of Excessive Somnolence-complications

12 záznamů v Medvik Filtry

Článek online

Idiopathic hypersomnia years after the diagnosis

Šonka, Karel
Autor Autorita ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Feketeová, Eva
Autor Autorita ORCID Department of Neurology, Faculty of Medicine, University of P.J. Šafárik and University Hospital of L. Pasteur, Košice, Slovak Republic
Nevšímalová, Soňa
Autor Autorita ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Horvat, Eszter Maurovich
Autor Horvat, Eszter Maurovich ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Příhodová, Iva
Autor Autorita ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Dostálová, Simona
Autor Autorita ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Galušková, Karolína
Autor Galušková, Karolína ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Milata, Martin
Autor Milata, Martin ORCID Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Bušková, Jitka
Autor Bušková, Jitka ORCID National Institute of Mental Health, Klecany and Third Faculty of Medicine, Charles University, Prague, Czech Republic
Susta, Marek
Autor Susta, Marek ORCID St. Elisabeth University, Bratislava, Slovak Republic

Journal of sleep research. 2024 ; 33 (2) : e14011. [pub] 20230812

J Sleep Res
ISSN 1365-2869
Medvik
Zdroj

Little attention has been paid to the long-term development of idiopathic hypersomnia symptoms and idiopathic hypersomnia comorbidities. The aim of this study was to describe the general health of patients with idiopathic hypersomnia years after the initial diagnosis, focusing on current subjective hypersomnolence and the presence of its other possible causes. Adult patients diagnosed with idiopathic hypersomnia ≥ 3 years ago at sleep centres in Prague and Kosice were invited to participate in this study. A total of 60 patients were examined (age 47.3 ± SD = 13.2 years, 66.7% women). In all participants, their hypersomnolence could not be explained by any other cause but idiopathic hypersomnia at the time of diagnosis. The mean duration of follow-up was 9.8 + 8.0 years. Fifty patients (83%) reported persisting hypersomnolence, but only 33 (55%) had no other disease that could also explain the patient's excessive daytime sleepiness and/or prolonged sleep. In two patients (3%), the diagnosis in the meantime had changed to narcolepsy type 2, and 15 patients (25%) had developed a disease or diseases potentially causing hypersomnolence since the initial diagnosis. Complete hypersomnolence resolution without stimulant treatment lasting longer than 6 months was reported by 10 patients (17%). To conclude, in a longer interval from the diagnosis of idiopathic hypersomnia, hypersomnolence may disappear or may theoretically be explained by another newly developed disease, or the diagnosis may be changed to narcolepsy type 2. Thus, after 9.8 years, only 55% of the examined patients with idiopathic hypersomnia had a typical clinical picture of idiopathic hypersomnia without doubts about the cause of the current hypersomnolence.

MeSH
dospělí MeSH
idiopatická hypersomnie * diagnóza epidemiologie farmakoterapie MeSH
komorbidita MeSH
lidé středního věku MeSH
lidé MeSH
narkolepsie * diagnóza epidemiologie MeSH
poruchy nadměrné spavosti * diagnóza epidemiologie komplikace MeSH
pozornost MeSH
Check Tag
dospělí MeSH
lidé středního věku MeSH
lidé MeSH
mužské pohlaví MeSH
ženské pohlaví MeSH
Publikační typ
časopisecké články MeSH

Článek online

Self-reported symptoms and objective measures in idiopathic hypersomnia and hypersomnia associated with psychiatric disorders: a prospective cross-sectional study

Journal of clinical sleep medicine. 2022 ; 18 (3) : 713-720. [pub] 20220301

J Clin Sleep Med
ISSN 1550-9397
Medvik
Zdroj

STUDY OBJECTIVES: In some patients, it is difficult to correctly nosologically classify daytime sleepiness. Clinical manifestations may be nonspecific; on the basis of objective measures it is possible to determine the current severity of sleepiness, but they do not always allow accurate diagnosis. It is especially difficult to distinguish between idiopathic hypersomnia (IH) and hypersomnia associated with a psychiatric disorder (PSY). METHODS: To find significant differences between the IH and PSY groups, we included 67 patients (IH, n = 15; PSY, n = 52) in the study, focusing on differences in self-reported symptoms, evaluating current depressive symptoms using the Beck Depression Inventory-II score and personality traits measured by the Temperament and Character Inventory. All of the patients underwent polysomnography, the Multiple Sleep Latency Test, and ad libitum sleep monitoring. RESULTS: The patients with IH showed greater difficulty than those in the PSY group with waking up in the morning (P < .001) and complained of memory (P = .04) and attention deficit (P = .006). They also showed higher total sleep time (P < .001) and sleep efficiency (P = .007) and a shorter mean sleep latency on the Multiple Sleep Latency Test (P < .001). Nevertheless, the IH and PSY groups did not differ in Beck Depression Inventory scores or personality characteristics. CONCLUSIONS: IH is a syndrome in which depression/external life stressors and personality characteristics also play a role. Patients with IH may benefit from the cooperation of sleep specialists with psychotherapists/psychiatrists. CITATION: Bušková J, Novák T, Miletínová E, et al. Self-reported symptoms and objective measures in idiopathic hypersomnia and hypersomnia associated with psychiatric disorders: a prospective cross-sectional study. J Clin Sleep Med. 2022;18(3):713-720.

MeSH
duševní poruchy * komplikace MeSH
idiopatická hypersomnie * komplikace diagnóza psychologie MeSH
lidé MeSH
narkolepsie * komplikace MeSH
poruchy nadměrné spavosti * komplikace diagnóza MeSH
prospektivní studie MeSH
průřezové studie MeSH
zpráva o sobě MeSH
Check Tag
lidé MeSH
Publikační typ
časopisecké články MeSH
práce podpořená grantem MeSH

Kapitola

Spojené poruchy spánku a jedení

Šonka, Karel, 1957-
Autor Autorita ORCID Neurologická klinika 1. LF UK a VFN v Praze

Anorexie, bulimie a psychogenní přejídání. 2018 ; () : 311-320.

ISBN 978-80-204-4904-7
Medvik
Zdroj

Článek

Vliv běžně užívaných antidepresiv na spánek u pacientů s depresivní poruchou
[Efffect of commonly used antidepressants on sleep in patients with depression]

Váňová, Šárka
Autor Váňová, Šárka Národní ústav duševního zdraví, Klecany

Psychiatrie (Praha, Print). 2016 ; 20 (2) : 108-112.

ISSN 1211-7579
Medvik
Zdroj

Článek online

Poruchy spánku u Parkinsonovy nemoci
[Sleep disturbances in Parkinson's disease]

Neurologie pro praxi. 2013 ; 14 (6) : 305-308.

Neurol. praxi
ISSN 1213-1814
Medvik
Zdroj

Poruchy regulace cyklu spánku a bdění patří mezi nejčastější a nejvíce omezující non-motorické příznaky Parkinsonovy nemoci (PN), postihují 50–95 % pacientů. Jejich etiologie je multifaktoriální, mezi nejvýznamnější příčiny patří primární spánkové poruchy, vedlejší účinky medikace, motorické příznaky PN přetrvávající v noci, psychiatrické komorbidity a neurodegenerace mozkových oblastí regulujících cyklus spánek-bdění. Doposud bylo provedeno velmi málo kontrolovaných studií se zaměřením na terapii spánkových poruch a léčba je tedy individuální s přihlédnutím ke komorbiditám a preferenci pacienta.

Sleep-Wake disturbances belong to the most common and disabling nonmotor symptoms of Parkinson‘s disease (PD) as they affect 50–95% patients. Etiology of impaired sleep and wakefulness in PD is multifactorial. Its most important causes are co-existent primary sleep disorders, medication side effects, overnight re-emergence of motor symptoms, psychiatric comorbidities and primary neurodegeneration of sleep regulating brain areas itself. To date, very few controlled studies are available to make a recommendation for their management, thus treatment of sleep-wake disturbances in PD must be tailored individually with respect to presence of comorbidities and patients preferences.

Článek

Sleep disorders and daytime sleepiness in children with attention-deficit/hyperactivity disorder: a two-night polysomnographic study with a multiple sleep latency test

Sleep medicine. 2010 ; 11 (9) : 922-928.

Sleep Med
ISSN 1389-9457
Medvik
Zdroj

OBJECTIVE: To evaluate sleep macrostructure, sleep disorders incidence and daytime sleepiness in attention-deficit/hyperactivity disorder (ADHD) affected children compared with controls. METHODS: Thirty-one patients (26 boys, 5 girls, mean age 9.3+1.7, age range 6-12 years) with ADHD diagnosed according to DSM-IV criteria, without comorbid psychiatric or other disorders, as never before pharmacologically treated for ADHD. The controls were 26 age- and sex-matched children (22 boys, 4 girls, age range 6-12 years, mean age 9.2+1.5). Nocturnal polysomnography (PSG) was performed for two nights followed by the multiple sleep latency test (MSLT). RESULTS: No differences between the two groups comparing both nights were found in the basic sleep macrostructure parameters or in the time (duration) of sleep onset. A first-night effect on sleep variables was apparent in the ADHD group. Occurrence of sleep disorders (sleep-disordered breathing [SDB], periodic limb movements in sleep [PLMS], parasomnias) did not show any significant differences between the investigated groups. A statistically significant difference (p=0.015) was found in the trend of the periodic limb movement index (PLMI) between two nights (a decrease of PLMI in the ADHD group and an increase of PLMI in the control group during the second night). While the mean sleep latency in the MSLT was comparable in both groups, children with ADHD showed significant (sleep latency) inter-test differences (between tests 1 and 2, 1 and 4, 1 and 5, p<0.01). CONCLUSION: After the inclusion of adaptation night and exclusion of psychiatric comorbidities, PSG showed no changes in basic sleep parameters or sleep timing, or in the frequency of sleep disorders (SDB, PLMS) in children with ADHD compared with controls, thus not supporting the hypothesis that specific changes in the sleep macrostructure and sleep disturbances are connected with ADHD. A first-night effect on sleep variables was apparent only in the ADHD group. Though we found no proof of increased daytime sleepiness in children with ADHD against the controls, we did find significant vigilance variability during MSLT in the ADHD group, possibly a sign of dysregulated arousal.