V článku je podán ucelený pohled na problematiku karcinomu mléčné žlázy se zaměřením na jeho léčbu s dělením do kapitol podle přítomnosti vzdálené diseminace, léčbě karcinomu prsu u těhotných žen, karcinomu prsu u mužů a zmíněn je přístup k jedincům s BRCA pozitivitou. Snahou bylo podat spíše zobecňující pohled na tuto obsáhlou problematiku.
In this article there is a complete look at breast cancer focused on its treatment. It is divided into chapters by the presence of distantmetastasis, the treatment of breast cancer in pregnant women and breast cancer in men. Approach to BRCA positive patients ismentioned too. The effort was to give generalised view on this comprehensive issue.
- MeSH
- Chemotherapy, Adjuvant methods trends utilization MeSH
- Surgical Procedures, Operative methods trends utilization MeSH
- Diagnostic Techniques and Procedures standards instrumentation utilization MeSH
- Drug Therapy methods trends utilization MeSH
- Genetic Predisposition to Disease MeSH
- Genes, BRCA1 MeSH
- Genes, BRCA2 MeSH
- Immunotherapy methods trends utilization MeSH
- Humans MeSH
- Mammography methods trends utilization MeSH
- Mastectomy classification methods trends MeSH
- Menstruation Disturbances complications MeSH
- Interdisciplinary Communication MeSH
- Breast Neoplasms epidemiology etiology therapy MeSH
- Neoadjuvant Therapy methods utilization MeSH
- Parturition physiology genetics immunology MeSH
- Radiotherapy methods trends utilization MeSH
- Risk Factors MeSH
- Statistics as Topic MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Anti-HER2 léčba pertuzumabem a trastuzumabem u časného karcinomu prsu snižuje riziko relapsu onemocnění o 1 % proti samotnému trastuzumabu při mediánu sledování 45,4 měsíce.
Anti-HER2 treatment with pertuzumab and trastuzumab in early breast cancer reduces the risk of relapse by 1 % against trastuzumab alone at median follow‑up of 45.4 months.
- MeSH
- Chemotherapy, Adjuvant methods utilization MeSH
- Contraception methods utilization MeSH
- Biological Therapy methods trends utilization MeSH
- Surgical Procedures, Operative * methods utilization MeSH
- Heredity genetics MeSH
- Diagnostic Techniques and Procedures * MeSH
- Hormone Replacement Therapy methods adverse effects MeSH
- Disease Attributes MeSH
- Humans MeSH
- Mammography methods trends utilization MeSH
- Menstruation MeSH
- Meta-Analysis as Topic MeSH
- Breast Neoplasms * diagnosis etiology classification MeSH
- Obesity MeSH
- Mass Screening methods trends utilization MeSH
- Radiotherapy methods utilization MeSH
- Risk Factors MeSH
- Statistics as Topic MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
- MeSH
- Biopsy methods MeSH
- Chest Pain diagnosis MeSH
- Histological Techniques utilization MeSH
- Antineoplastic Agents, Hormonal administration & dosage pharmacology therapeutic use MeSH
- Humans MeSH
- Mammography utilization MeSH
- Breast Neoplasms * diagnosis drug therapy MeSH
- Aged, 80 and over MeSH
- Tamoxifen pharmacology therapeutic use MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Aged, 80 and over MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Early Diagnosis MeSH
- Diagnostic Imaging methods trends utilization MeSH
- Genetic Phenomena physiology genetics immunology MeSH
- Gynecology * methods trends MeSH
- Disease Attributes * MeSH
- Colorectal Surgery methods utilization MeSH
- Colorectal Neoplasms diagnosis etiology surgery MeSH
- Humans MeSH
- Mammography methods utilization MeSH
- Minimally Invasive Surgical Procedures methods trends utilization MeSH
- Breast Neoplasms diagnosis surgery MeSH
- Postoperative Period MeSH
- Preventive Medicine methods trends MeSH
- Recurrence MeSH
- Robotic Surgical Procedures * utilization MeSH
- Statistics as Topic MeSH
- Check Tag
- Humans MeSH
- Publication type
- Interview MeSH
Screening nádorů prsu je jedinou ověřenou metodou snižování úmrtnosti na karcinom prsu. Samovyšetřování prsu je přes existenci mamografie a ultrazvukových vyšetření stále nezbytnou součástí prevence karcinomu prsní žlázy u žen ve fertilním věku i žen po menopauze. Nositeli edukace o prevenci by se vedle dobrovolnic z pacientských organizací měli opět stát i zdravotníci.
Mammographic screening is the only reliable method for reduction of mortality from breast cancer. Self-examination is still, despite of mammography and ultrasound examination, the basic method for breast cancer prevention in women in fertile age as well as a complimentary method for post-menopausal women. Education about breast cancer prevention with regard to self-examination is also an equally important issue for volunteers as for medical professionals.
- MeSH
- Child MeSH
- Humans MeSH
- Mammography methods utilization MeSH
- Breast Neoplasms * prevention & control MeSH
- Primary Prevention MeSH
- Breast Self-Examination methods MeSH
- Ultrasonics methods MeSH
- Patient Education as Topic MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Review MeSH
Screening nádorů prsu je jedinou ověřenou metodou snižování úmrtnosti na karcinom prsu. V České republice existuje celoplošný auditovaný screening od roku 2003. Do konce roku 2014 bylo v ČR mamograficky vyšetřeno 5 546 037 žen, u 28 813 participantek byl odhalen zhoubný nádor, ve většině případů v časných stadiích s velmi úspěšnou léčbou a dobrou prognózou. Od roku 2003 do konce roku 2009 měly na pravidelné a bezplatné vyšetření jednou za dva roky nárok ženy ve věkové skupině 45 až 69 let. Od roku 2010 mají do screeningu přístup všechny ženy starší 45 let bez omezení horní věkové hranice. Účast žen ve screeningu přestoupila již v roce 2008 přes hranici 50 %, v roce 2014 dosáhla 62,8 %. Efektivita screeningu, nárůst proporce časných stadií a redukce úmrtnosti na karcinom prsu jsou pravidelně auditovány a vyhodnocovány z dat sbíraných ze všech 70 screeningových center.
Mammographic screening is the only reliable method for reduction of mortality from breast cancer. In the Czech Republic a countrywide mammographic screening has been in function since 2003. Th us, 5 546 037 women have been mammographically examined till the end of 2014 with 28 813 breast cancers detected, vast majority of them in early stages with a good chance for effective therapy and excellent prognosis. In the years 2003–2009 regular and health insurance paid examinations were available to women in age 45–69. Since 2010 mammographic screening has been extended beyond 69 years of age with no upper limit. Th e participation of Czech women in mammographic screening exceeded 50 % already in 2008, in 2014 reached even 62,8%. Effectiveness of screening, increasing proportion of early stages and reduction of breast cancer mortality have been regularly audited and evaluated based on data collected from all 70 Czech breast cancer screening units.
- MeSH
- Patient Compliance MeSH
- Accreditation trends utilization legislation & jurisprudence MeSH
- Humans MeSH
- Mammography * methods trends utilization MeSH
- Breast Neoplasms * diagnosis epidemiology prevention & control MeSH
- Mass Screening * economics trends utilization MeSH
- Registries MeSH
- Quality Control MeSH
- Secondary Prevention MeSH
- Statistics as Topic MeSH
- Government Programs MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Geographicals
- Czech Republic MeSH
- Keywords
- diskrepance měření velikosti nádorů, multifokální karcinom prsu, multicentrický karcinom prsu,
- MeSH
- Early Detection of Cancer MeSH
- False Positive Reactions MeSH
- Carcinoma diagnosis pathology therapy MeSH
- Congresses as Topic * MeSH
- Magnetic Resonance Imaging * classification methods standards instrumentation trends utilization MeSH
- Mammography * ethics classification methods standards utilization MeSH
- Breast Neoplasms diagnosis epidemiology classification therapy MeSH
- Breast anatomy & histology MeSH
- Stress, Psychological MeSH
- Truth Disclosure ethics MeSH
- Ultrasonography, Mammary * methods standards utilization MeSH
- Physician-Patient Relations MeSH
- MeSH
- Biological Therapy methods trends utilization MeSH
- Cyclin-Dependent Kinases antagonists & inhibitors therapeutic use MeSH
- Genetic Predisposition to Disease genetics prevention & control MeSH
- Genetic Therapy methods trends utilization MeSH
- Genes, BRCA1 MeSH
- Genes, BRCA2 MeSH
- Precision Medicine * methods trends utilization MeSH
- Humans MeSH
- Mammography methods trends utilization MeSH
- Mastectomy methods trends utilization MeSH
- Breast Neoplasms * diagnosis etiology prevention & control MeSH
- Mass Screening * methods utilization MeSH
- Motor Activity MeSH
- Cancer Vaccines MeSH
- Statistics as Topic MeSH
- Life Style MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Interview MeSH
- Geographicals
- Czech Republic MeSH
