Možnost řešení objemné ureterokély v dětském věku. Prezentujeme kazuistiku chlapce, který byl na našem pracovišti operován pro ureterokélu s mnohočetnou ureterolitiázou.
The possibility of solving a bulky uretererocele in childhood. We present a case report of a boy who was operated on at our institution for ureterocele with multiple ureterolithiasis.
- MeSH
- Diagnostic Techniques, Urological MeSH
- Child MeSH
- Endoscopy methods MeSH
- Humans MeSH
- Nephrolithiasis therapy MeSH
- Ureterocele * diagnostic imaging diagnosis complications therapy MeSH
- Urolithiasis diagnostic imaging therapy MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Case Reports MeSH
- Research Support, Non-U.S. Gov't MeSH
- MeSH
- Diagnosis, Differential MeSH
- Child MeSH
- Hydronephrosis complications MeSH
- Humans MeSH
- Infant, Newborn, Diseases MeSH
- Infant, Newborn MeSH
- Ultrasonography, Prenatal MeSH
- Ureterocele * diagnostic imaging congenital MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
AIM: To assess of the role of renal ultrasonography (US) and DMSA renal scintigraphy in the prediction of irreversible histological lesions of the upper pole in duplex system. METHODS: A prospective cohort study based on data collected between 2005 and 2012 at our institution. The cohort consisted of 23 patients with ureteroceles and 28 patients with ectopic ureters who underwent upper pole nephrectomy. Preoperative recordings from ultrasound and nuclear renal scans were compared with the histological findings. Histological irreversible lesions were defined as the presence of dysplasia and/or severe chronic interstitial nephritis (CIN) in ≥ 90% of the specimen. ROC (Receiver Operating Characteristic) curves were used to investigate thresholds in order to identify irreversible lesions using various differential functions. The histology was correlated with the results of imaging. RESULTS: Pathological findings were found in all histological samples. Histological lesions were irreversible in 20/23 patients (87.0%) with ureteroceles and in 14/28 patients (50.0%) with ectopic ureters. The model is able to predict irreversible lesions if an upper pole differential function is ≤ 3% in patients with ureteroceles, and ≤ 2% in the presence of ectopic ureters. Weak association between parenchymal thinning on ultrasonography and irreversible lesions was found in patients with ectopic ureters. CONCLUSION: DMSA renal scintigraphy provides a useful tool for the prediction of irreversible lesions in the upper pole. Low differential function (≤ 3% and ≤ 2%, respectively) indicates irreversible lesions, favoring heminephrectomy. Higher differential function indicates greater remaining biological potential of the parenchyma, favoring reconstruction of the upper pole.
- MeSH
- Child MeSH
- Infant MeSH
- Succimer MeSH
- Kidney abnormalities MeSH
- Humans MeSH
- Child, Preschool MeSH
- Prospective Studies MeSH
- Radionuclide Imaging MeSH
- ROC Curve MeSH
- Ultrasonography MeSH
- Ureter abnormalities MeSH
- Ureterocele diagnostic imaging MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Male MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Evaluation Study MeSH
- Comparative Study MeSH