V posledních letech vzrostla v populaci obliba rostlinných přípravků, protože jsou pacienty považovány za čistě přírodní, a proto bezpečné. Rostlinné výtažky jsou také obsaženy v běžně používané kosmetice. Riziko alergických reakcí je zvýšené u osob s atopickým ekzémem, alergickou rýmou a průduškovým astmatem. Nejčastěji dochází k rozvoji alergické kontaktní dermatitidy. Anafylaxe se objevuje výjimečně. Kazuistika pojednává o anafylaxi ve vazbě na lokální aplikaci dužiny z listů aloe pravé u dospívající dívky po předchozí senzibilizaci kosmetickými krémy s obsahem aloe vera.
Medicinal remedies of plant origin became very popular in recent years, and are considered to be „naturally safe“ by many patients. Herbal extracts are commonly used in cosmetics. The risk of allergic reactions to these is increased in patients suffering from allergic rhinoconjunctivitis, bronchial asthma and atopic dermatitis. Allergic contact dermatitis is the most frequently reported side effect, whereas anaphylaxis is considered rare. The case report presents a case of anaphylaxis due to local application of Aloe vera leave pulp in a pubertal girl after previous sensitization to cosmetics containing extracts of Aloe vera.
- MeSH
- Dermatitis, Allergic Contact diagnosis etiology immunology MeSH
- Hypersensitivity complications MeSH
- Aloe * immunology adverse effects MeSH
- Anaphylaxis * diagnosis etiology immunology MeSH
- Administration, Topical MeSH
- Humans MeSH
- Adolescent MeSH
- Drug-Related Side Effects and Adverse Reactions classification MeSH
- Plant Preparations classification adverse effects MeSH
- Check Tag
- Humans MeSH
- Adolescent MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Epinephrine administration & dosage therapeutic use MeSH
- Hypersensitivity drug therapy complications MeSH
- Anaphylaxis * diagnosis etiology drug therapy MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Alergie na domácí zvířata je spojena s velkým rizikem rozvoje alergické rýmy a astmatu. Senzibilizace alergeny kočky je v populaci velmi rozšířená, dokonce i u lidí, kteří nikdy sami kočku nechovali. Bylo popsáno několik alergenních molekul z různých zdrojů (srst, sliny, moč a produkty kožních žláz), z nichž některé zkříženě reagují s alergeny jiných zvířat. Klinicky nejvýznamnější je alergen Fel d 1, na který rea- guje až u 96 % alergických pacientů. Vzhledem k významu Fel d 1 je diagnostika alergie na kočku jednodušší než u jiných zvířat. Podrobné vyšetření dalších alergenních molekul je přínosné u pacientů s polyvalentní alergií a má význam pro predikci tíže a charakteru alergických potíží. Důležitou součástí terapie je eliminace alergenu kočky, která je však v praxi obtížně proveditelná. Obvykle je doporučována kombinace různých opatření, vedoucích k omezení množství alergenu v prostředí. U některých pacientů byl pozorován přechodný rozvoj tolerance vlastního zvířete při trvalé expozici. Alergenová imunoterapie kvalitním, standardizovaným alergenovým extraktem může v indikovaných případech vést k redukci symptomů a zvýšení kvality života.
Allergy to pets represents a great risk for developing respiratory allergic disease. The sensitizaton to cat is very frequent in the population even in people who had never cat in their homes. Several allergenic molecules have been identified from different sources (dander, saliva, urine and skin glands), some of them having cross-reactivity with other mammalian allergens. The most important cat allergen is Fel d 1 to which up to 96% of allergic patients react. Due to this fact the diagnosis of cat allergy is more simple than in other mammalian. The more precise molecular diagnostic is usefull in pollyallergic patients and in prediction of the disease severity and the risk of asthma developing. Elimination of the cat allergen as an important part of the therapy is difficult to realise. Combination of several metodes of diminution quantitiy of allergen at home is recommended, but none of them is fully effective. In some patients the tolerance of their own animal can develop in the time of high exposure to cat allergens, but it is usually temporary. Allergen immunotherapy with standardised allergenic extract can bring reduction of symptoms and improvement of quality of life even if the contact with cat continues.
- MeSH
- Allergens MeSH
- Hypersensitivity * diagnosis complications prevention & control therapy MeSH
- Desensitization, Immunologic methods MeSH
- Immunologic Tests methods MeSH
- Cats MeSH
- Humans MeSH
- Dander immunology MeSH
- Check Tag
- Cats MeSH
- Humans MeSH
- Publication type
- Review MeSH
- Keywords
- benralizumab,
- MeSH
- Hypersensitivity diagnosis drug therapy immunology complications MeSH
- Biological Therapy methods MeSH
- Asthma * drug therapy immunology complications MeSH
- Eosinophilia MeSH
- Antibodies, Monoclonal, Humanized * administration & dosage MeSH
- Comorbidity MeSH
- Middle Aged MeSH
- Humans MeSH
- Treatment Failure MeSH
- Obesity complications MeSH
- Prednisone administration & dosage MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- Keywords
- dupilumab,
- MeSH
- Rhinitis, Allergic complications MeSH
- Hypersensitivity drug therapy complications MeSH
- Dermatitis, Atopic drug therapy complications MeSH
- Biological Therapy * MeSH
- Asthma * drug therapy complications MeSH
- Adult MeSH
- Adrenal Cortex Hormones therapeutic use MeSH
- Antibodies, Monoclonal, Humanized administration & dosage economics MeSH
- Comorbidity MeSH
- Humans MeSH
- Nasal Polyps complications MeSH
- Disease Progression MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Adrenergic beta-2 Receptor Agonists therapeutic use MeSH
- Hypersensitivity drug therapy complications MeSH
- Muscarinic Antagonists therapeutic use MeSH
- Asthma drug therapy MeSH
- Bronchodilator Agents * therapeutic use MeSH
- Pulmonary Disease, Chronic Obstructive * diagnosis drug therapy MeSH
- Drug Combinations MeSH
- Cigarette Smoking adverse effects MeSH
- Middle Aged MeSH
- Humans MeSH
- Treatment Outcome MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- Keywords
- alergická (eozinofilní) kolitida,
- MeSH
- Hypersensitivity diagnosis immunology complications MeSH
- Biomarkers blood urine MeSH
- Diet * methods utilization MeSH
- Gastroenterology MeSH
- Endoscopy, Gastrointestinal methods utilization MeSH
- Gastrointestinal Hemorrhage * diagnosis etiology therapy MeSH
- Histological Techniques utilization MeSH
- Infant MeSH
- Breast Feeding methods adverse effects MeSH
- Colitis * diagnosis etiology therapy MeSH
- Humans MeSH
- Prognosis MeSH
- Ultrasonography methods utilization MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Case Reports MeSH
Alergické choroby postihujú približne jednu tretinu populácie, pričom obvykle vyžadujú pravidelnú aplikáciu antialergickej liečby, vrátane alergénovej imunoterapie. Alergici a pacienti s chronickými alergickými respiračných chorobami nemajú na základe doposiaľ publikovaných údajov výraznejšie zvýšené riziko závažného ochorenia COVID-19 v porovnaní s bežnou populáciou. Lieky používané v liečbe alergií (s vý-nimkou systémových kortikoidov) nepredstavujú žiadne riziko vo vzťahu k vzniku a komplikovanému priebehu ochorenia COVID-19. Pacienti majú pokračovať vo svojej chronickej antialergickej liečbe (vrátane biologík, imunosupresív či kortikoidov) bez jej prerušovania či znižovania dávky. To platí aj pre alergénovú imunoterapiu, v ktorej má pacient ďalej pokračovať. Ak sa u alergika potvrdí COVID-19, je nevyhnutné kontaktovať ošetrujúceho špecialistu s vysoko individuálnym prehodnotením ďalšej terapeutickej stratégie alergického ochorenia. Cieľom je udržanie dosiahnutej kontroly nad alergickým ochorením.
Allergic diseases affect one third of general population and usually require regular application of anti-allergic treatment of allergen immuno-therapy. Allergic people and patients with chronic allergic respiratory diseases, based on the published studies and case report series, do not yield an increased risk for obtaining COVID-19 compared to the general population. Anti-allergic medicaments /with the exception of systemic corticosteroids) do not represent a risk in relation with COVID-19 and its complicated course. Patients should continue in their chronic anti-allergic treatment (including biologicals, immunosuppressants, and corticosteroids) without the withdrawal or tapering the dose. Patients should continue also in the applied allergen immunotherapy. In case of acquiring COVID-19, it is necessary to contact the caring specialists with the highly-individualized re-assessment of the therapeutic strategy. The aim is to maintain the achieved control over allergic disease.
- Keywords
- Covid 19, eozinopenie,
- MeSH
- Hypersensitivity * drug therapy complications therapy MeSH
- Angiotensin-Converting Enzyme 2 MeSH
- COVID-19 * immunology complications MeSH
- Desensitization, Immunologic MeSH
- Eosinophils pathology MeSH
- Humans MeSH
- Respiratory Tract Diseases epidemiology MeSH
- Risk MeSH
- Risk Factors MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Keywords
- vedolizumab,
- MeSH
- Hypersensitivity complications MeSH
- Bariatric Surgery MeSH
- Gastroesophageal Reflux MeSH
- Gastrointestinal Agents administration & dosage adverse effects MeSH
- Antibodies, Monoclonal, Humanized administration & dosage adverse effects MeSH
- Clinical Studies as Topic MeSH
- Clinical Trials, Phase III as Topic MeSH
- Comorbidity MeSH
- Diabetes Complications MeSH
- Humans MeSH
- Multicenter Studies as Topic MeSH
- Pancreatic Neoplasms epidemiology prevention & control MeSH
- Obesity complications MeSH
- Risk Factors MeSH
- Irritable Bowel Syndrome MeSH
- Colitis, Ulcerative drug therapy MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Keywords
- pylová sezóna, orální alergický syndrom, ITUZALAX,
- MeSH
- Allergens administration & dosage adverse effects therapeutic use MeSH
- Conjunctivitis, Allergic drug therapy complications MeSH
- Hypersensitivity epidemiology drug therapy complications MeSH
- Betula adverse effects MeSH
- Desensitization, Immunologic * methods MeSH
- Adult MeSH
- Clinical Trials, Phase III as Topic MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Multicenter Studies as Topic MeSH
- Pollen adverse effects MeSH
- Rhinitis, Allergic, Seasonal etiology drug therapy complications MeSH
- Sublingual Immunotherapy MeSH
- Treatment Outcome MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Geographicals
- Europe MeSH
