An analytical method for the determination of the composition of renal stones by capillary isotachophoresis with conductometric detection was developed. Using different leading/terminating electrolyte systems, the qualitative and quantitative analysis of organic compounds (urate, xanthate, oxalate) and inorganic ions (phosphate, Ca(2+), Mg(2+), Na(+), NH(4)(+)) species commonly present in mixed renal stones in three separate steps can be carried out with limits of detection about 10 μmol/L. The developed method was validated by the analysis of real samples and can be used for urinary calculi classification. In addition, it was verified that this method can also be employed for the determination of the above mentioned analytes in some other samples (bones, teeth) concerning apatite biominerals (fluoro-, carbonate-, chloro-apatite).

• MeSH
• anionty moč   MeSH
• apatity chemie   MeSH
• fosfáty moč   MeSH
• izotachoforéza metody   MeSH
• kationty dvojmocné moč   MeSH
• kationty jednomocné moč   MeSH
• konduktometrie MeSH
• kosti a kostní tkáň chemie   MeSH
• kyselina močová moč   MeSH
• ledvinové kameny chemie   MeSH
• lidé MeSH
• limita detekce MeSH
• oxaláty moč   MeSH
• soli moč   MeSH
• uhličitany moč   MeSH
• zuby chemie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

• MeSH
• diabetes insipidus diagnóza   farmakoterapie   MeSH
• dítě MeSH
• poruchy močení etiologie   MeSH
• soli moč   nedostatek   terapeutické užití   MeSH
• Check Tag
• dítě MeSH
• Publikační typ
• kazuistiky MeSH