- MeSH
- Durapatite MeSH
- Calcinosis diagnosis classification therapy MeSH
- Publication type
- Review MeSH
- MeSH
- Apatites MeSH
- Adult MeSH
- Middle Aged MeSH
- Lysosomes physiopathology MeSH
- Joint Diseases pathology ultrastructure MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Male MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
V předložené práci se zabýváme studiem kvality povrchu modelu titanového implantátu povlečeného laserově deponovanou vrstvou hydroxyapatitu s mezivrstvou zirkonu. Povrch byl hodnocen in vitro, tedy lidské liniové fibroblasty povrch buněk kolonizují a množí se na něm, aniž by buňky vykazovaly morfologické změny. Studie hodnotí nový materiál jako vhodný pro implantaci s možností okamžitého zhotovení protetické náhrady.
The study investigated the quality of surface of titanium implant model, covered by laser-deposed layer of hydroxyapatite with a zirconium inter-layer. The surface was evaluated in vitro, human line fibroblasts therefore colonized the surface and multiplied there without displaying morphological changes. The study evaluates the new material as a suitable one for implantation with possibilities of immediate production of prosthetic substitution.
- MeSH
- Fibroblasts physiology MeSH
- Research Support as Topic MeSH
- Durapatite therapeutic use MeSH
- Ceramics therapeutic use MeSH
- Humans MeSH
- Titanium therapeutic use MeSH
- Zirconium therapeutic use MeSH
- Dental Implants MeSH
- Dental Materials MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
- Comparative Study MeSH
Práce se zabývá zejména studiem biologických vlastností modelu implantátu povlečeného tenkou vrstvou hydroxyapatitu s mezivrstvou zirkonu. Hodnotící metodou je přímý test cytotoxicity provedený kultivací s myšími a lidskými fibroblasty. Dále byl proveden fyzikální test k analýze a složení krystalové struktury filmu (RTG difrakce), který potvrdil, že se jedná o krystalický hydroxyapatit. Zhodnocením testu cytotoxicity a srovnáním s kontrolními, paralelně kultivovanými vzorky in vitro, docházíme k závěru, že materiál není cytotoxický a je vhodný k dalším detailnějším pokusům.
The paper deals primarily with the study of biological properties of a model of implant covered with a thin layer of hydroxyapatite with an intermediate layer of zirconium. Cytotoxicity was evaluated by direct cultivation with mouse and human fibroblasts. A physical test using X-ray diffraction confirmed that the film is composed of crystalline hydroxyapatite. The evaluation of the cytotoxicity test and a comparison with controlled samples cultured in parallel in vitro made it possible to conclude that the material is not cytotoxic audit is suitable for further experiments in more detail.
- MeSH
- X-Ray Diffraction methods instrumentation MeSH
- Fibroblasts MeSH
- Research Support as Topic MeSH
- Durapatite therapeutic use MeSH
- Humans MeSH
- Mice MeSH
- Toxicity Tests methods MeSH
- Titanium therapeutic use MeSH
- Zirconium therapeutic use MeSH
- Dental Implants MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Review MeSH
- Comparative Study MeSH
- MeSH
- Biocompatible Materials administration & dosage MeSH
- Child MeSH
- Adult MeSH
- Durapatite administration & dosage therapeutic use MeSH
- Collagen administration & dosage therapeutic use MeSH
- Bone Cysts diagnosis surgery MeSH
- Rabbits MeSH
- Humans MeSH
- Bone Neoplasms diagnosis surgery MeSH
- Animals MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Rabbits MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- MeSH
- Research Support as Topic MeSH
- Durapatite chemistry therapeutic use MeSH
- Dental Implants methods MeSH
- Dental Materials MeSH
- Publication type
- Review MeSH
Acta orthopaedica Scandinavica ; Supplement Vol. 64. 255
58 s. : obr., tab. ; 25 cm
- MeSH
- Biocompatible Materials MeSH
- Hydroxyapatites MeSH
- Prostheses and Implants MeSH
- Dogs MeSH
- Foreign-Body Reaction MeSH
- Check Tag
- Dogs MeSH
- Conspectus
- Lékařské vědy. Lékařství
- NML Fields
- ortopedie
- transplantologie
