As a result of the findings of scientists working on the biosynthesis and metabolism of steroids in the plant and animal kingdoms over the past five decades, it has become apparent that those compounds that naturally occur in animals can also be found as natural constituents of plants and vice versa, i.e., they have essentially the same fate in the majority of living organisms. This review summarizes the current state of knowledge on the occurrence of animal steroid hormones in the plant kingdom, particularly focusing on progesterone, testosterone, androstadienedione (boldione), androstenedione, and estrogens.

• MeSH
• androstadieny metabolismus   MeSH
• androstendion biosyntéza   MeSH
• biosyntetické dráhy MeSH
• estrogeny biosyntéza   MeSH
• fytosteroly metabolismus   MeSH
• progesteron biosyntéza   MeSH
• rostliny metabolismus   MeSH
• steroidy biosyntéza   MeSH
• testosteron biosyntéza   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

• MeSH
• androstadieny metabolismus   terapeutické užití   MeSH
• aplikace inhalační MeSH
• beklomethason imunologie   metabolismus   terapeutické užití   MeSH
• bronchiální astma farmakoterapie   terapie   MeSH
• budesonid terapeutické užití   MeSH
• dítě MeSH
• farmakologické účinky MeSH
• fluocinolonacetonid aplikace a dávkování   terapeutické užití   MeSH
• hormony kůry nadledvin aplikace a dávkování   škodlivé účinky   terapeutické užití   MeSH
• lidé MeSH
• pregnendiony terapeutické užití   MeSH
• triamcinolon terapeutické užití   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• Publikační typ
• směrnice pro lékařskou praxi MeSH

beta-catenin has a dual function; it is implicated in intercellular junctions and transcriptional co-activation. Here we examined the regulation of the expression and localization of beta-catenin in HT29 colorectal adenocarcinoma cells. Our results showed that inhibition of PI-3 kinase with wortmannin was accompanied by a considerably reduced expression of beta-catenin. This effect was overcome by butyrate and occurred at the protein level, not at the level of mRNA. Moreover, NaBT significantly increased the phosphorylation of the ribosomal protein, S6, known to participate in the translational control of gene expression. This was accompanied by the increased phosphorylation of p70 S6K and MAPKs, the effector proteins that are upstream of protein S6 in the distinct signaling pathways. These facts indicate that different signaling pathways may be involved in the regulation of beta-catenin synthesis. Modulation of beta-catenin expression induced by NaBT appeared to occur at the level of protein translation, suggesting that NaBT may act as a translational regulator.

• MeSH
• adenokarcinom metabolismus   MeSH
• alkalická fosfatasa metabolismus   MeSH
• androstadieny metabolismus   MeSH
• beta-katenin genetika   metabolismus   MeSH
• butyráty metabolismus   MeSH
• financování organizované MeSH
• fosfatidylinositol-3-kinasy metabolismus   MeSH
• fosforylace MeSH
• imunohistochemie MeSH
• inhibitory fosfoinositid-3-kinasy MeSH
• kinasy ribozomálního proteinu S6, 70-kDa metabolismus   MeSH
• kinasy ribozomálního proteinu S6 metabolismus   MeSH
• kolorektální nádory metabolismus   MeSH
• lidé MeSH
• mitogenem aktivované proteinkinasy metabolismus   MeSH
• nádorové buněčné linie MeSH
• serin metabolismus   MeSH
• signální transdukce fyziologie   MeSH
• tyrosin metabolismus   MeSH
• Check Tag
• lidé MeSH