We aimed to describe facial directional asymmetry (DA) in individuals with different manifestations of laterality. Due to the overlap between brain and face development, a relationship between the manifestation of brain laterality and DA is hypothesised. These findings could clarify the relationship between the brain and facial phenotype and help to plan facial or oral motor rehabilitation. The DA of 163 healthy individuals was assessed by two complementary 3D methods: landmark and polygonal surface analysis using colour-coded maps. Handedness was assessed using the Edinburgh Handedness Inventory, while chewing side and eye preferences were self-reported. The results showed a similar DA pattern regardless of sex and laterality (the right-sided protrusion of the forehead, nose, lips, and chin) and a slightly curved C-shape of the midline in landmark analysis. A relationship between lateralized behaviours and DA was found only in males, in females the DA pattern was more homogenous. Right-handed individuals and right-side chewers showed a protrusion of the right hemiface. Males, left-handed and left-side chewers, manifested a protrusion of the left lateral hemiface. We suggest that these specific differences in males may be due to their typically higher level of brain asymmetry. No apparent relationship was found between eyedness and DA.
- MeSH
- asymetrie obličeje * patofyziologie MeSH
- dospělí MeSH
- funkční lateralita * fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- obličej fyziologie MeSH
- žvýkání * fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Development of the craniofacies occurs in embryological intimacy with development of the brain and both show normal left-right asymmetries. While facial dysmorphology occurs to excess in psychotic illness, facial asymmetry has yet to be investigated as a putative index of brain asymmetry. Ninety-three subjects (49 controls, 22 schizophrenia, 22 bipolar disorder) received 3D laser surface imaging of the face. On geometric morphometric analysis with (x, y, z) visualisations of statistical models for facial asymmetries, in controls the upper face and periorbital region, which share embryological intimacy with the forebrain, showed marked asymmetries. Their geometry included: along the x-axis, rightward asymmetry in its dorsal-medial aspects and leftward asymmetry in its ventral-lateral aspects; along the z-axis, anterior protrusion in its right ventral-lateral aspect. In both schizophrenia and bipolar disorder these normal facial asymmetries were diminished, with residual retention of asymmetries in bipolar disorder. This geometry of normal facial asymmetries shows commonalities with that of normal frontal lobe asymmetries. These findings indicate a trans-diagnostic process that involves loss of facial asymmetries in both schizophrenia and bipolar disorder. Embryologically, they implicate loss of face-brain asymmetries across gestational weeks 7-14 in processes that involve genes previously associated with risk for schizophrenia.
- MeSH
- asymetrie obličeje * diagnostické zobrazování patologie MeSH
- bipolární porucha * diagnostické zobrazování patologie MeSH
- dospělí MeSH
- funkční lateralita fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mozek diagnostické zobrazování patologie MeSH
- obličej MeSH
- psychotické poruchy diagnostické zobrazování patologie MeSH
- schizofrenie * diagnostické zobrazování patologie MeSH
- zobrazování trojrozměrné MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Tremor is commonly found among healthy humans or prevalently a symptom of neurological dysfunctions. However, the distinction between physiological and pathological tremor is dependent on the examiner's competence. Archimedes Spiral Rating (ASR) is a valid and reproducible semi-quantitative method to assess the severity of action tremor. OBJECTIVES: (1) To assess the range and percentiles of ASR in a large sample seemingly free of tremor-related conditions or symptoms from the population-based CHRIS-study. (2) To analyze the influence of sex, age, and the drawing hand on ASR. (3) To define ASR limits of normal. (4) To supply exemplary Archimedes spiral drawings by each rating to favor consistent and proficient clinical evaluation. METHODS: Accurately investigated participants were randomly sampled over 14 sex-age strata. 2686 paired spirals drawn with both hands by 1343 participants were expertly assessed on a tremor rating scale from 0 to 9. RESULTS: ASR had a quadratic increase with age in both sexes, while it was relatively lower in the dominant compared to the non-dominant hand and in women compared to men. ASRs above sex-age specific 97.5th percentiles of 4 and 5, below and above 60 years of age, respectively, were conceivably of non-physiological nature. CONCLUSIONS: In a large population-based sample we show a steeper increase of action tremor by age as age progresses. Relatively higher ratings among the elderly, males and the non-dominant hands, appear compatible with ASR limits of "normal" across sex-age groups. The current operational evidence may support practitioners differentiating physiological and pathological hand tremor.
- MeSH
- dospělí MeSH
- funkční lateralita fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- referenční hodnoty MeSH
- ruka fyziologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sexuální faktory MeSH
- stupeň závažnosti nemoci MeSH
- tremor * patofyziologie diagnóza MeSH
- věkové faktory MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- apraxie diagnóza klasifikace patologie MeSH
- diagnostické techniky neurologické klasifikace MeSH
- funkční lateralita fyziologie MeSH
- lidé MeSH
- motorické dovednosti * fyziologie MeSH
- neurologické poruchy chůze etiologie klasifikace patologie MeSH
- poruchy motorických dovedností * diagnóza klasifikace patofyziologie MeSH
- psychomotorické poruchy diagnóza MeSH
- zrcadlové neurony fyziologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
Ballet training has been reported to positively influence balance ability. It is not entirely clear how improved balance ability manifests under standing conditions with different demands on postural control. The aim of the study was to compare balance of ballet dancers and non-dancers in a unipedal stance under different conditions. Twenty-five professional ballet dancers and twenty-five controls completed four unipedal standing balance tests: firm surface with eyes open and closed; foam mat surface with eyes open; and firm surface with eyes open immediately after performing ten 360° whole-body turns. The centre of pressure (COP) data were obtained with a force platform and the direction-specific standard deviations, velocities, and sample entropy of the COP displacement were computed. A three-way analysis of variance was used to compare groups, genders, and conditions. For standing immediately after performing ten turns, the postural sway parameters were significantly larger in the control group compared to the ballet dancers in both men and women. In this stance condition the values of postural sway and COP velocities in the control group were larger in the men compared to the women. For both genders in the control group all postural sway and COP velocity parameters were larger in standing with eyes closed and standing after performing 10 turns compared to standing with eyes open on both firm and foam surface. In the ballet dancers all COP velocity parameters were larger in standing with eyes closed compared to all other conditions. The results from the present study indicate that professional ballet dancers do not have a better general balance ability than untrained subjects.
- MeSH
- dospělí MeSH
- funkční lateralita fyziologie MeSH
- lidé MeSH
- mladý dospělý MeSH
- postura těla fyziologie MeSH
- posturální rovnováha fyziologie MeSH
- tanec fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
Tato přehledová studie se zaměřuje na fenomén laterality obecně i na její konkrétní formy, což jsou leváctví a asymetrie mozko- vých hemisfér. Autorka se snaží se tyto pojmy definovat, popsat a vysvětlit případný vztah mezi vedoucí rukou a asymetrií hemisfér, konkrétně specializovaných funkčních oblastí v mozku člověka. Ve studii jsou nastíněny teorie, které řeší otázku, proč lateralita rukou a mozku evolučně vznikla a z jakých důvodů se vyvine u jedince, a to z hlediska genetických příčin i možného vlivů prostředí. Studie následně popisuje leváctví a praváctví v lidské populaci, klasifikaci laterality rukou u člověka a možnosti, jak vedoucí ruku určit.
The review focuses on the phenomenon of laterality in general and also it focuses on specific forms of laterality that are handed- ness and the asymmetry of brain hemispheres. The author tries to define the terms, describe the phenomena and explain a potential relation- ship between the dominant hand and the asymmetry of brain hemispheres, specifically the asymmetry of specialized functional areas in the human brain. There are theories presented in the study that try to answer a question why the laterality of hands and brain evolved. Theories about mechanisms of how laterality can develop at an individual level are presented too, both from genetic and environmental points of view. Study subsequently describes handedness among human population, classification of the laterality of hands and ways how one can tell which hand is the dominant one.
The term laterality indicates the one-sided preference or functional advantage of the stronger, more accurate and coordinated limbs or organs and the brain hemisphere of a human body. In the prefe-rence process, more accurate, precise, coordinated and stronger side is chosen from the perspective of motoric functions. Among the general population is about 10–13% of left-handers and in certain sport fields this percentage may be higher (baseball, tennis, box etc.). The left-handed dominance in tennis is considered an advantage. Due to unilateral load, there may be an excessive side-effect in strength differences in tennis and overloading of specific muscle group could lead to an injury. The aim of the research was to identify the levels of somatic and strength characteristics and assess the lateral diffe-rence in maximal grip strength of Czech elite male tennis players. The sample consisted of male tennis players, ranging in age from 11 to 12.9 years (n = 186) who participated in the regular tests for Czech Tennis Association in years 2000–2018. Base anthropometrics were measured (height, weight) and ma-ximal grip strength of both hands using the hand-held dynamometry (Grip D). Data came from normal distribution (statistically proven – chi-square test). The basic statistical characteristics were calculated (body height, M = 155.08 ± 7.98 cm; body weight, M = 43.45 ± 7.13 kg; strength of right hand: M = 24.88 ± 4.67 kp; strength of left hand: M = 21.70 ± 4.74 kp). It was found that 87.6% of the players (n = 163) were right-handed and the remaining 12.4% left-handed (n = 23). The assessment of the significance (Cohen’s d) between the dominant (playing) hand for the right-handed and left-handed players showed small effect size (dominant hand right: MRHR = 25.11 ± 4.41 kp, dominant hand left: MLHL = 26.62 ± 5.65 kp; d = 0.30, small) in favor of the left-handed players. The difference between the dominant and the non-dominant hand showed large effect size for the right-handed (dominant hand right vs. hand left; MRHR = 25.11 ± 4.41 kp, MRHL = 21.01 ± 4.15 kp, d = 0.96, large) and medium effect size for the left-handed players (dominant hand left vs. hand right; MLHL = 26.62 ± 5.65 kp, MLHR = 23.24 ± 5.98 kp, d = 0.58, medium). The results showed that the value of 15 % level of strength laterality between dominant and non-dominant hand was exceeded for the right-handed (55.83 %) and left-handed (43.48%) groups ergo the exceeded value could be a cause of injuries. Because of this signals attention should be given during training process for optimizing the required load.
- MeSH
- dítě MeSH
- funkční lateralita fyziologie MeSH
- lidé MeSH
- poranění ruky prevence a kontrola MeSH
- síla ruky * MeSH
- svalová síla - dynamometr statistika a číselné údaje MeSH
- tenis * fyziologie statistika a číselné údaje zranění MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Geografické názvy
- Česká republika MeSH
Cognitive control processes play an essential role not only in controlling actions but also in guiding attentional selection processes. Interestingly, these processes are strongly affected by organizational principles of the cerebral cortex and related functional asymmetries, but the neurobiological foundations are elusive. We ask whether neurobiological mechanisms that affect functional cerebral asymmetries will also modulate effects of top-down control processes on functional cerebral asymmetries. To this end, we examined potential effects of the imprinted gene leucine-rich repeat transmembrane neuronal 1 (LRRTM1) on attentional biasing processes in a forced attention dichotic listening task in 983 healthy adult participants of Caucasian descent using the "iDichotic smartphone app." The results show that functional cerebral asymmetries in the language domain are associated with the rs6733871 LRRTM1 polymorphism when cognitive control and top-down attentional mechanisms modulate processes in bottom-up attentional selection processes that are dependent on functional cerebral asymmetries. There is no evidence for an effect of LRRTM1 on functional cerebral asymmetries in the language domain unrelated to cognitive control processes. The results suggest that cognitive control processes are an important factor to consider when being interested in the molecular genetic basis of functional cerebral architecture.
- MeSH
- akustická stimulace metody MeSH
- dospělí MeSH
- funkční lateralita fyziologie MeSH
- jazyk (prostředek komunikace) MeSH
- kognice fyziologie MeSH
- lidé MeSH
- membránové proteiny genetika MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mozková kůra fyziologie MeSH
- pozornost fyziologie MeSH
- proteiny nervové tkáně genetika MeSH
- průzkumy a dotazníky MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: There are several cortical areas related to the limbic system that form the output from the hippocampal formation whose cellular and morphological features are important for the onset and progression of AD. We hypothesized that there would be a significant difference in the size of cortical pyramidal neurons and that there would also be a hemispheric asymmetry between Alzheimer disease patients and controls. These differences would potentially be accompanied by an increase in the numbers of Fluoro-Jade B-positive degenerating cortical neurons and a corresponding decrease in the numbers of DAPI-stained cortical neuronal nuclei in subjects with AD compared to controls. Such changes could potentially be used as another marker in postmortem neuropathological diagnosis of AD. METHODS: We measured absolute numbers of DAPI and Fluoro-Jade B stained cells in five cortical areas of the limbic system and four subareas of planum temporale in the post-mortem brains of subjects with Alzheimer disease. We also measured the size of pyramidal neurons in layer III in the five cortical areas of the limbic system in these subjects. All measurements were performed separately for the left and right hemisphere in order to identify asymmetries between the two hemispheres. RESULTS: We observed a significant decrease in numbers of DAPI stained cells in layers IV-VI of the anterior cingulate gyrus on the right side, in layers I-III of the posterior cingulate gyrus on the left side, in layers IV-VI in the transition region from superior temporal gyrus into planum temporale on the right and in layers IV-VI in the transition from planum temporale to insular cortex on the left. We also observed a significant increase in the numbers of Fluoro-Jade stained cells in layers I-III of the anterior cingulate gyrus and in layers I-III on the left and layers IV-VI of the right gyrus of Heschl. Shortening of the size of layer III pyramidal neurons in subjects with Alzheimer´s disease was found in the anterior cingulate gyrus on the right, in the posterior cingulate gyrus and entorhinal cortex on the left and on the right in the parahippocampal gyrus. CONCLUSION: Our study demonstrates asymmetries in different cortical regions of the temporal lobe that can be used as another marker in the postmortem diagnosis of AD.
- MeSH
- Alzheimerova nemoc patologie MeSH
- cingulární gyrus patologie MeSH
- fluoresceiny metabolismus MeSH
- funkční lateralita fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mapování mozku * MeSH
- počet buněk MeSH
- pyramidové buňky patologie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- spánkový lalok patologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
