Among ochratoxins, ochratoxin A (OTA) occupies a dominant place and represents significant risk for human and animal health which also implies economic losses around the world. OTA is nephrotoxic, hepatotoxic, teratogenic and immunotoxic mycotoxin. OTA exposure may lead to formation of DNA adducts resulting to genotoxicity and carcinogenicity (human carcinogen of 2B group). Now it seems that OTA could be "a complete carcinogen" which obliges to monitor its presence in biological materials, especially using the suitable biomarkers. In this article, OTA findings in urine, blood, serum, plasma and human kidneys (target dose) in the Czech Republic and comparison with foreign countries are presented.

• MeSH
• karcinogeny metabolismus   farmakokinetika   toxicita   MeSH
• kontaminace potravin MeSH
• ledviny účinky léků   MeSH
• lidé MeSH
• mateřské mléko metabolismus   MeSH
• nemoci ledvin etiologie   MeSH
• ochratoxiny metabolismus   farmakokinetika   toxicita   MeSH
• tkáňová distribuce MeSH
• vystavení vlivu životního prostředí MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH
• Geografické názvy
• Česká republika MeSH