The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic sequencing (along with other genome-wide molecular assays) and increasing evidence of its clinical utility will soon drive the generation of sequence data from tens of millions of humans, with increasing levels of diversity. In this perspective, we present the GA4GH strategies for addressing the major challenges of this data revolution. We describe the GA4GH organization, which is fueled by the development efforts of eight Work Streams and informed by the needs of 24 Driver Projects and other key stakeholders. We present the GA4GH suite of secure, interoperable technical standards and policy frameworks and review the current status of standards, their relevance to key domains of research and clinical care, and future plans of GA4GH. Broad international participation in building, adopting, and deploying GA4GH standards and frameworks will catalyze an unprecedented effort in data sharing that will be critical to advancing genomic medicine and ensuring that all populations can access its benefits.
- Publikační typ
- časopisecké články MeSH
We investigate the state of multilingualism across the social sciences and humanities (SSH) using a comprehensive data set of research outputs from seven European countries (Czech Republic, Denmark, Finland, Flanders [Belgium], Norway, Poland, and Slovenia). Although English tends to be the dominant language of science, SSH researchers often produce culturally and societally relevant work in their local languages. We collected and analyzed a set of 164,218 peer-reviewed journal articles (produced by 51,063 researchers from 2013 to 2015) and found that multilingualism is prevalent despite geographical location and field. Among the researchers who published at least three journal articles during this time period, over one-third from the various countries had written their work in at least two languages. The highest share of researchers who published in only one language were from Flanders (80.9%), whereas the lowest shares were from Slovenia (57.2%) and Poland (59.3%). Our findings show that multilingual publishing is an ongoing practice in many SSH research fields regardless of geographical location, political situation, and/or historical heritage. Here we argue that research is international, but multilingual publishing keeps locally relevant research alive with the added potential for creating impact.
- Publikační typ
- časopisecké články MeSH
A common Authentication and Authorisation Infrastructure (AAI) that would allow single sign-on to services has been identified as a key enabler for European bioinformatics. ELIXIR AAI is an ELIXIR service portfolio for authenticating researchers to ELIXIR services and assisting these services on user privileges during research usage. It relieves the scientific service providers from managing the user identities and authorisation themselves, enables the researcher to have a single set of credentials to all ELIXIR services and supports meeting the requirements imposed by the data protection laws. ELIXIR AAI was launched in late 2016 and is part of the ELIXIR Compute platform portfolio. By the end of 2017 the number of users reached 1000, while the number of relying scientific services was 36. This paper presents the requirements and design of the ELIXIR AAI and the policies related to its use, and how it can be used for serving some example services, such as document management, social media, data discovery, human data access, cloud compute and training services.
- Klíčová slova
- GA4GH, GDPR, IAM, authentication, authorisation, data access,
- MeSH
- biomedicínský výzkum metody MeSH
- lidé MeSH
- software * MeSH
- systémy řízení databází * MeSH
- uživatelské rozhraní počítače MeSH
- výpočetní biologie metody MeSH
- výzkumní pracovníci MeSH
- zabezpečení počítačových systémů * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
